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Natural Science Forum / Biology / Biology / April 2006How much $ to sequence my genome?
Just out of curiosity, I was wondering about the concept of human genome project. Whose genome was sequenced by human genome project? Did many different humans contributed? How much would it cost to me to get the sequence of my own genome? The short answer... A LOT! A lot of money and a lot of time. A good sequencer will do about 3 million bases a day. Considering the genome is 6 billion bases (2 sets of chromosomes), that wouuld roughly equal about 6 years to finish, just once. Cost would equal around $11 million. In all reality, one would need to sequence the genome about 2 to 3 times to get an accurate map. So your cost then doubles, triples or quadruples. (This is assuming you had the $500,000 DNA sequencer). Technology is getting a lot cheaper and faster, but not ever at a level where it would become practical for individuals to sequence their own genomes. What you would find is that your genome is quite similar to the already published genome. Just look for the hot spots of > Just out of curiosity, I was wondering about the concept of human > genome project. Whose genome was sequenced by human genome project? Did > many different humans contributed? How much would it cost to me to get > the sequence of my own genome? >The short answer... A LOT! A lot of money and a lot of time. > [quoted text clipped - 7 lines] >where it would become practical for individuals to sequence their own >genomes. I agree with most of that, until the last point. Getting sequencing cost down to $1000 for a genome is a current goal of those working on genomics technology. New techniques are in the wings -- even beginning to be used. It remains to be seen how this will play out, and how long it will take. Advances in technology are not easily predicted. But don't be too pessimistic. "Not ever" is a long time. bob |
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