(snip)
> Well, now it is somehow more clear. Now I understand your point of
> view.
[quoted text clipped - 3 lines]
> are organic creature made of proteins and nucleic acid and has no cell
> structure. They are able to reproduce by infecting LIVING cells. So
Yes, I agree, but no-one has ever done an exhaustive and detailed
experiment of taking every known virus and culturing them and then
pairing each of them together to see if any kill its pair mate. For
example, putting the HIV virus together with Influenza A virus. Do they
get along with one another or does one kill the other.
Let us say the world has 2,000 viruses. Culture every one of them. Then
pair them up and see if some bizarre unexpected result occurs such as
one killing another virus. There just maybe a possibility of creating a
virus that eats other viruses.
Perhaps the world has no such viricide as yet because we have not done
such an experiment to coax and urge a virus to Reassort itself to
becoming a killer of other viruses.
> then, viruses are inexorable innercellular parasites reproducing by
> using copying mechanism included in cells they infect. They contain
> genetical material (RNA or DNA), but they demonstrate both living and
> inanimate matter.
Well it maybe the case that virus Q kills other viruses just by some
interaction or stops other viruses from reproducing. Perhaps the 1918
Spanish flu was stopped due to the large prescence of some other virus
by 1918. Maybe what stops viral pandemics is the rise of another virus
that suppresses the once dominant virus. Perhaps that is why birdflu
sort of lay low from 1918 to 2006 because of the presence of some other
rising star virus. Perhaps most viruses emit some molecule which
suppresses other viruses.
Perhaps viruses in their lifecycle of infecting a host emit and shed
parts of their anatomy which inhibits other viruses. Much like black
walnut trees emit a herbicide juglone which thwarts the growth of other
plants nearby. So maybe viruses emit molecules that are viral
suppressants..
> Also, there is a problem in viruses size. Maybe virus can infect other
> virus, but they should differ much in its size (ex. herpes- and
[quoted text clipped - 7 lines]
> like reversed transcriptase, but it doesn't really change the
> impossibility of an occurrence you want to induct or observe.
I was thinking along the lines of how white blood cells attack and kill
a virus. They sometimes cut apart the virus. Or they surround and
engulf the virus. Now we find the genomic sequence that cuts apart a
virus in the white blood cell and we attempt to Reassort this sequence
of cutting apart into a virus. We sort of graft the cutting or
engulfing into a species of virus in hopes that the new virus will go
around attacking other viruses and kill them.
I do not much care for a virus killer to reproduce itself. All I want
is the trait of killing other viruses.
> Second case is what you said about viruses infecting for example only
> cells of human cancer. It is generally one of the main developed and
[quoted text clipped - 6 lines]
> recontruct virus' capsomeres and genes you want to be inserted to
> cancer cell (sequentions inducting the apoptosis).
I am mainly looking to see if any virus kills or inhibits other
viruses. I believe there has been little to no study as to the
behaviour of interactions of all the known viruses when paired in one
culture. Whether any virus kills or causes the other paired virus to go
dormant.
And by using Reassortment, I believe this technique allows us to create
viruses that do just about anything we want. So a virus that kills only
specific cancer cells would be a generalization of the viricide. And
the fact that the viricide or cancercide cannot reproduce itself is a
bonus in that we can control it better.
> Note that I am not a virusologist and can be wrong, but I wanted to
> explain this problem as good as I can. Forgive my - sometimes -
> terrible english.
Your english is very good.
Archimedes Plutonium
www.iw.net/~a_plutonium
whole entire Universe is just one big atom
where dots of the electron-dot-cloud are galaxies
blount7@gmail.com - 19 Jul 2006 08:23 GMT
> (snip)
> >
[quoted text clipped - 97 lines]
> whole entire Universe is just one big atom
> where dots of the electron-dot-cloud are galaxies
T virus, G virus? and I just started playing Resident Evil 2 recently!
lol! Anyway, I agree that there has been very little research on virus
interaction in one single culture.
>"Well it maybe the case that virus Q kills other viruses just by some interaction or stops other viruses from reproducing."
I think this is the most plausible way that a virus killing virus would
go about killing other viruses. Interfering with thier reproduction,
the most vital function.
Here is a link about above stated virus vs. cancer techniques.
http://www.popsci.com/popsci/medicine/2ab7c4522fa84010vgnvcm1000004eecbccdrcrd.html
Good points, all around! I think your on to something.
a_plutonium@hotmail.com - 19 Jul 2006 20:50 GMT
(snipped to save space)
> T virus, G virus? and I just started playing Resident Evil 2 recently!
> lol! Anyway, I agree that there has been very little research on virus
[quoted text clipped - 10 lines]
>
> Good points, all around! I think your on to something.
Good reference site. So they call this techniqe virotherapy.
--- quoting in parts some of the above website ---
Biotechnology
Can a Virus Kill Cancer?
Genetic engineers are turning nasty, infectious microbes into smart
treatments for a deadly disease
By Joshua Tomkins April 2005
In February, researchers at UCLA announced a clash of the titans,
biochemically speaking: They turned one of the great scourges of
humankind-HIV-into a hunter of another: cancer. In tests on mice
afflicted with metastatic melanoma, a modified strain of HIV invaded
cancer cells without infecting the rodents with AIDS. Around the same
time, researchers at the Mayo Clinic in Rochester, Minnesota, announced
similar results after engineering the measles virus to seek and destroy
cancerous tumors while leaving healthy tissue unscathed.
The close timing of these breakthroughs speaks to the flurry of
activity in the field of virotherapy, which exploits the tendency of
viruses to attack cancer cells in a pitched battle that cancer often
loses. With preliminary studies showing many of these viruses to be
safe for humans, several universities and biotech firms are now
conducting clinical trials of virotherapy.
As radical as it sounds, the idea of turning viruses loose on cancer
actually predates the genetic technology that now fuels it. During the
1950s, scientists proved that adenovirus, a version of the common cold
bug, was mildly effective against cervical cancer. But research was
abandoned as chemotherapy gained prominence, and virotherapy was
resurrected only after a study published in the journal Science in 1991
showed that a virus could be genetically modified to invade a tumor
without inflicting disease.
(snipped)
Likewise, the HIV strain in the UCLA melanoma study was targeted, and
researchers have since tailored it to seek and destroy prostate and
melanoma cancers. "Basically, we put different hooks on the virus so
it can hold on to different molecules," says Irvin S.Y. Chen,
director of the UCLA AIDS Institute.
(snipped)
--- end quoting in parts ---
I wanted to include some of the history of this technique. History is
important in understanding.
As the poster also reasserted my claim that researchers have never
really delved into the issue of virus to other viral interactions. We
simply have little knowledge on this and are mostly in the dark.
What would happen if we create a huge massive culture and added every
known virus into this culture. Would one virus emerge as the conqueror
virus. Would one virus produce some sort of suppressant that kills or
stagnates all other viruses. Is there a virus that acts like penicillin
to other viruses. Our knowledge and understanding of viral interactions
is crude and primitive.
We are missing many answers as to why the 1918 birdflu virus
disappeared or stagnated for the past 90 years and is just recently
emerged. Could it be that some other virus in the past 90 year interval
suppressed birdflu? Perhaps some common cold virus suppresses H5N1.
I note that some males in Vietnam are immune to H5N1. Could it be that
this person has some other virus in his body that confers that
immunity. Perhaps some hepatitis virus or some other virus confers
immunity to H5N1.
If that is true in part or whole, we need to find out about this as the
most important defense and weapon to use on H5N1 to stop it from going
pandemic.
Archimedes Plutonium
www.iw.net/~a_plutonium
whole entire Universe is just one big atom
where dots of the electron-dot-cloud are galaxies