#61 updated TV show "The Forgetting (Alzheimers) ; new book: Metal Causation coupled with Weak-Protein-Point ^Theory of Medicine (Alzheimers, Autism, Parkinsons, Prion, Schizophrenia)
|
|
Thread rating:  |
Archimedes Plutonium - 09 Aug 2008 09:16 GMT I hope I have my numbers correct, for I have many books ongoing and hope that this is actually #61.
Tonight in the late hours of the morning I saw this excellent TV show on PBS of the Alzheimers disease. It is this show that taught me the basic mechanics of the disease of Alzheimers that the APP scissors is rogue and cuts the APP protein wrongly, leaving a small beta amyloid plaque. Actually, the first airing of The Forgetting showed this mechanism better for in this updated version it was spoken of by Dr. Tanzi as to this mechanism. Trouble is that Dr. Tanzi is tilted too far into the idea that Alzheimers is a genetic disease.
Alzheimers and the other 4 diseases this book covers is caused by metal or chemical poisons.
I hope researchers start looking and examining the APP scissors as the essential key to the whole disease. As of this date, everyone seems to focus on either the beta amyloid plaques or the tau protein buildup.
Logically, it is the APP scissors that should be the central focus.
So what can cause a scissors to become so rogue that it makes bad cuts in the APP? It is not genetic, but rather, obviously, some chemical poison. Perhaps some form of a mercury compound. Perhaps mercury in conjunction with fluoride.
Granted, it was the genetics of chromosome 21 that Tanzi studied that lead us to the APP scissors. But now is the time to drop the genetics and focus on the scissors.
This updated version of "The Forgetting" was good in that it relayed the news of what is called the Pittsburgh Compound that allows us to actually see the beta amyloid plaques in the brain. Every tool we have increases our knowledge of what is going on. But now I wonder of several questions about the Pittsburgh Compound: (1) Can we design a compound that sticks to the APP scissors? (2) Has anyone actually retrieved an APP scissors that is rogue and making those beta amyloid particles? One of the scientist in the show said these beta amyloids were about the size of two red blood cells contiguous.
So what I am thinking is that if we can devise another Compound similar to the Pittsburgh Compound that sticks to the rogue scissors of APP that we could actually cure the Disease of Alzheimers altogether.
For consider this: that if we can identify rogue APP scissors and then find a compound that sticks to only rogue scissors and thereby those scissors could never produce another beta amyloid particle, and whereby the body cleans out these rogue APP-scissors with the attached Compound. And further yet, devise another Compound that sticks to the beta amyloid and flushes it out of the system. So that we made great progress with the Pittsburgh Compound but it should be utilized further than merely identification of beta amyloid but actually as a treatment itself. So the bulk of the labor is to get rid of the rogue APP scissors and then get rid of the beta amyloid thereby conquering Alzheimers.
Finally, the program mentioned a nice and easy test to tell if one has Alzheimers. Ask a person if they can spell a word, such as World and then ask them to spell that word backwards. A normal mind can do that with almost any word, but an Alzheimers cannot spell backwards.
I expect in the next 5 years when they do a third version of the Forgetting on PBS TV that this time they will focus on the APP scissors and focus on what chemicals of the environment for the past 107 years, where this version told of the history of Dr. Alzheimer treating a Mrs. Augustin De (spelling) in the year 1901.
Why the sudden huge rise of Alzheimers in the 20th century? Not because of genetics, but because the increasing rise of some chemical poisons such as mercury and the overabundance of fluoride in the drinking water.
So take out a rogue APP scissors and find out how it became rogue. Was it mercury-fluoride or hydrofluoric acid? Or some other chemicals that turns normal scissors into rogue scissors.
P.S. I also want to make mention of some odd curious fact about Alzheimers that does not appear in the 4 other diseases listed. The fact that there seems to be two proteins gone awry in Alzheimers the beta amyloid and the tau protein. So why two rogue proteins? Is the rogue APP scissors responsible for the tau protein also? So our research has not really gone very far into these questions as to why two rogue proteins.
But the TV show is an A+ program that should be continued and updated.
Archimedes Plutonium www.iw.net/~a_plutonium whole entire Universe is just one big atom where dots of the electron-dot-cloud are galaxies
plutonium.archimedes@gmail.com - 09 Aug 2008 18:48 GMT > I hope I have my numbers correct, for I have many books ongoing and > hope that this is actually #61. [quoted text clipped - 80 lines] > > But the TV show is an A+ program that should be continued and updated. I had a look through Google as to the situation of China's Alzheimers, because if it is mercury that is making rogue APP-scissors then China should have the world's highest rate of Alzheimers. And that is what I found in this BBC report:
--- quoting BBC news --- That is because she is one of China's six million sufferers of Alzheimer's. The country now has a third of all Alzheimer's patients in the world. And the number of diagnosed cases is rising. --- end quoting BBC news ---
I also worry about the Olympic atheletes at the games of 2008 in Beijing because all it really takes is a lungful of mercury to catch Alzheimers.
Also, the rate of Alzheimers in China would not be an easy data to find as that China would probably practice euthanasia.
The link between coal fired electric power stations and Alzheimers is a mighty big link for it implies that the amount of mercury in the air is what deforms the APP- scissors.
And, as I have said before, if you look at the regions in the USA where the air is laden with the most mercury such as around Utah and Texas, you find the highest rates of Alzheimers disease.
Archimedes Plutonium www.iw.net/~a_plutonium whole entire Universe is just one big atom where dots of the electron-dot-cloud are galaxies
plutonium.archimedes@gmail.com - 09 Aug 2008 19:03 GMT (snipped)
> P.S. I also want to make mention of some odd curious fact about > Alzheimers that does not appear in the 4 other diseases listed. The fact > that there seems to be two proteins gone awry in Alzheimers the beta > amyloid and the tau protein. So why two rogue proteins? Is the rogue > APP scissors responsible for the tau protein also? So our research has > not really gone very far into these questions as to why two rogue proteins. On second thought, I do remember reading a report that in Prion disease there are a multitude of "forms" of the diseased prion protein. And in Parkinsons there is more rogue proteins than simply the alpha synuclein. It is just because in Alzheimers that two proteins of a distinct difference are noticed in the disease process.
So whether the rogue APP-scissors causes both the beta-amyloid particle and later causes the tau-protein-particle to form is a question open to research. Is the rogue APP-scissors the cause of both the rogue proteins? Perhaps the mercury compound that causes the rogue APP-scissors that causes the beta-amyloid-particle connects with some other chemical to cause the tau-particle. Is there some metal ion in the beta amyloid and in the tau-protein for which the mercury compound deforms?? Our current day research has not caught up with these questions.
But in Prion and Parkinsons, there are also more than one rogue protein involved, and so Alzheimers is not a divergent oddity as to multiple rogue proteins.
Trouble with all these 5 diseases is that no-one has spent as much time doing mass spectrography of mercury poisons, as they have spent time on genetics such as chromosome 21. If we could spend more research time on what deforms normal APP scissors into rogue APP-scissors we would be getting at the heart of Alzheimers.
Archimedes Plutonium www.iw.net/~a_plutonium whole entire Universe is just one big atom where dots of the electron-dot-cloud are galaxies
plutonium.archimedes@gmail.com - 10 Aug 2008 09:52 GMT Did some searching around for all the proteins implicated in Alzheimer, Parkinson and Prion.
Sorry about that, for Parkinson has 3 rogue proteins whereas Alzheimer has 2 rogue proteins of beta-amyloid and tau protein.
I was looking for the structure of the APP molecule and the APP- scissors to see if they contain copper. Apparently they do.
So what I am getting a preliminary picture of the structure of these diseases is that all the molecules involved in Alzheimer, Prion, Parkinson have copper ions as a core metal ion. We all know blood has iron as a core metal ion. But it appears that these three diseases of Alzheimer, Parkinsons and Prion have copper as their core metal ion.
As for Autism and Schizophrenia, I am not sure of whether there is a copper ion as the core of some protein molecule as the basis of those two diseases.
But let me float a preliminary speculative theory that would tie together all 5 diseases into one smooth working mechanism of the disease.
We all know that mercury in contact with gold or copper tends to amalgamate, meaning it binds, or has an attraction or changes the original shape of the central copper ion. So could it be that mercury, in various forms such as ethyl-mercury or methyl-mercury or other toxic forms that as it enters the brain can change the "shape or orientation" of the central copper ion in the various proteins or proteases of these 5 diseases. Now when the mercury changes the orientation, the mercury does not remain with that misshappened protein but moves onwards to encounter more of those proteins.
So in Alzheimers the mercury may misshappen the APP rather than the APP-scissors, and either way, if it misshapes the APP resulting in beta-amyloid stubs or whether the mercury misshapes the scissors which then produces the stubs is immaterial becuase either way there is a creation of unwanted and unremoval stubs of beta amyloid.
So let me make this rash speculation for it seems to tie everything together in these 5 diseases. They all involve some protein gone awry. And we all know mercury can deform proteins. So my conjecture here is that mercury deforming the metal ion that is central to the protein or protease such as copper. That the mercury via "force of amalgam" causes a deformation or misshaping of the molecule and which the body cannot correct that misshappened protein or protease.
The biggest problem I have with the above conjecture is why does not a person show signs of two or more of these diseases if mercury is the main culprit? That is a tough question. If the above is true, we should have people who have both Parkinsons and Alzheimers both simultaneously. Maybe we actually do have such cases. In my readings I found a Alzheimers called "Swedish mutation" and I found a Parkinsons called the "Iowan case". It appears we are finding more and more of these cases where we have accelerated Parkinsons or accelerated Alzheimers. Perhaps what these special cases are is a convergence of Parkinsons with Alzheimers. And as we find more exotic cases of these two diseases we end up with a victim who has both of them simultaneously.
It is good for me to proffer is overarching conjecture that the mercury misshapes the copper ion in these 5 diseases. We all know of sickle cell anemia caused by a misshappened iron in blood cells. So when one can offer an idea that answers 5 diseases all at once, it is best to offer it because it is rare in science that one mechanism can consolidate 5 disparate diseases, but since one mechanism can solve 5 disparate diseases there is a good chance that it is a true mechanism. It is sort of Occam's Razor of Logic turned around. That if you see one mechanism that can explain 5 disparate diseases-- take that plunge of a unification of those disparate 5 diseases for there is a good chance it is correct-- as Occam would say "a simple mechanism is likely to be true!!"
So here is my conjecture: we have 5 disparate diseases all involving the brain and we all know mercury is toxic and damaging to brain tissue and cells and proteins. All 5 diseases have proteins or proteases and all have copper ions as central metal ions. We all know that mercury has a force of attraction to copper called an amalgam-force. So the conjecture is that some form of mercury deforms proteins or proteases to cause these 5 diseases.
My toughest challenge is to explain why no person seems to have two or more of these diseases simultaneously. There probably have already been such cases but no-one really payed much attention to discovering or reporting them. In that PBS show where they showed some Alzheimers victims, it appears they have tremors and shaking as what goes on in Parkinsons in there final stages. Whether they have Lewy bodies in their brains is unknown to me.
Archimedes Plutonium www.iw.net/~a_plutonium whole entire Universe is just one big atom where dots of the electron-dot-cloud are galaxies
plutonium.archimedes@gmail.com - 10 Aug 2008 21:28 GMT This is a valid question and a challenge to the theory that mercury and other metal causation of these 5 diseases. If some poison metal causes these diseases we should expect some patients to have a mix of two or more of these diseases. We should have a Parkinsons showing signs of Alzheimers. Maybe there are such cases but not reported, not diagnosed, and not searched for.
In the past, I answered this question by saying there are various different metals involved and various different compounds so that Prion disease is cesium-mercury whereas Alzheimers is mercury-fluoride.
But maybe I can do better.
If we look at these 5 diseases listed we see a pattern. We see that the earliest of these diseases is Autism and the next one to appear in victims is Schizophrenia in the teens and 20's. The next to appear in a timeline is Parkinsons in the 50's and then Prion in the 60's and finally Alzheimers in the 70's. So the five listed diseases are a time progression of victimization.
So has anyone studied whether Autism and Schizophrenia are related in terms of frequency of appearance? Do autistic patients become schizophrenic or a high incidence? Do Parkinson's patients have a high frequency of going into Alzheimers? Prion disease is rare, but has anyone studied whether CJD goes into Alzheimers?
In this progression timeline of these 5 diseases ---> Autism ---> Schizophrenia ---> Parkinsons ---> Prion ---> Alzheimers
In that progression follows a progression of the brain region development. Autism is infants and the region of the brain being developed is the social region of communicating with others and that is the region damaged, and then next is schizophrenia and the region being developed in the brain at teenager and 20s is the neocortex and that is the region damaged by schizophrenia.
So in the progression timeline there is a pattern that the region being developed in the brain is the region that mercury would attack.
This suggests to me, that it can be mercury solely as the poisoning metal. Not that mercury goes to the region of the brain being developed but that mercury gets lodged into the DNA/RNA sequencing. Not that mercury gets lodged into the APP or the APP-scissors but that mercury gets lodged further upstream in the actual DNA/RNA sequencing.
So let us say you have a 3 year old and mercury enters their brain, then it goes and gets lodged into the DNA/RNA sequencing and the focus of development of a 3 year old is that part of the brain that is "social communication" and the mercury inters with that sequencing. Let us say you have a teenager who never had any mercury in their body but as a teenager comes in contact with mercury into the brain. As a teenager, the DNA/RNA sequencing has long past the "social development region of the brain" but is now focused on the neocortex of sequencing-development. So the mercury gets lodged into the DNA RNA sequencing and messes-up that development and the aftereffects end up with schizophrenia.
The same sort of picture emerges with a 50 year old in that mercury messes up the region where Parkinsons takes place. Likewise the Alzheimers region for 70 year olds.
In this fashion, mercury solo can be the cause of all 5 diseases. It would explain why there are hundreds of different disease shaped Prion proteins. It would explain why there are tens to hundreds of proteins involved in Parkinsons. As far as we know, in Alzheimers there are only two proteins involved of beta amyloid and tau-protein, but if one really checks into these two rogue proteins, they begin to see that each of them has tens to hundreds of "different versions".
So I used to explain this by saying there are tens to hundreds of different mercury compounds for there is ethyl-mercury and methyl-mercury and mercury-fluoride and mercury- cesium and mercury-rubidium etc etc.
Better yet, as the evidence and data show, that if you lodge, just simply mercury in the DNA/RNA sequencing that if this mercury is not dislodged but allowed to influence whatever is "in focus for the brain to develop" at that time of the patients life, then the solo mercury can cause all 5 of these diseases.
Here is an analogy of a gang of criminals as mercury and a day as a lifetime. In the early hours of the morning say from 1 am to 4 am the criminals are breaking and entering homes and stealing valuables (Autism), then from 5 am to 10 am the criminals are robbing people in the subways and commuter stations of their purses and wallets (Schizophrenia), then from 11 am to 3 pm they are robbing banks (Parkinsons). You catch my drift in this analogy. That solo mercury lodged in the DNA and RNA sequencing of the developing human brain from birth to age 70 can unfold these diseases.
P.S. Still it would be nice to see a report of a person who has two or more of these diseases simultaneously, for it would "qualitatively prove the mercury causation of these diseases".
Archimedes Plutonium www.iw.net/~a_plutonium whole entire Universe is just one big atom where dots of the electron-dot-cloud are galaxies
plutonium.archimedes@gmail.com - 11 Aug 2008 09:18 GMT Something I should have done before, made a Google search for patients with concomitant disease. Using the keywords of-- simultaneous Parkinson Alzheimer I got these hits:
1. Alzheimer's Symptoms www.aricept.com Learn About Signs & Symptoms. Diagnosis and Treatment Info.
Search Results Changes in the brain may link Alzheimer's and Parkinson's diseases ... both Alzheimer's disease and Parkinson's disease, supporting clinical observations of the simultaneous appearance of symptoms of both in some patients. ... www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1172958 - Similar pages - Note this
The Neurobiology of Parkinsons Disease, part 2: further research ... Interestingly though, both conditions carry symptoms of dementia. Recently there have been cases of simultaneous Parkinsons and Alzheimers symptoms (5). ... serendip.brynmawr.edu/exchange/node/1697 - 40k - Cached - Similar pages - Note this
Parkinson Studies Find More Apathy than Depression, Experience ... Jul 11, 2006 ... Go to more on Alzheimer's, Parkinson & Dementia or More Senior News on ... Because apathy and depression share some of the same symptoms, ... seniorjournal.com/NEWS/Alzheimers/6-07-11-ParkinsonStudies.htm - 59k - Cached - Similar pages - Note this
Brain changes may link Alzheimer's and Parkinson's diseases ... Brain changes may link Alzheimers and Parkinsons diseases from British Medical ... of the simultaneous appearance of symptoms of both in some patients. ... findarticles.com/p/articles/mi_m0999/is_7316_323/ai_n27571532 - 42k - Cached - Similar pages - Note this
Lower urinary tract symptoms in dementia with Lewy bodies ... Lower urinary tract symptoms in dementia with Lewy bodies, Parkinson disease, and Alzheimer disease. G. N. Ransmayr, MD, S. Holliger, MD, K. Schletterer, ... www.neurology.org/cgi/content/full/70/4/299?maxtoshow=&HITS=25&hits=25&RESULTFOR MAT=&ando... - Similar pages - Note this
Changes in the brain may link Alzheimer’s and Parkinson’s diseases ... Brain changes may link Alzheimer's and Parkinson's diseases ... clinical observations of the simultaneous appearance of symptoms of both in some patients. ... www.bmj.com/cgi/content/abridged/323/7316/771 - Similar pages - Note this
The Dana Foundation - A Novel Imaging Approach for Early Diagnosis ... The distinction between patients with Parkinson's disease who have concomitant Alzheimer disease, generally known as the Lewy Body Variant of AD (LBV-AD), ... www.dana.org/grants/imaging/detail.aspx?id=5886 - 54k - Cached - Similar pages - Note this
I did not find specific person names with concomitant disease but apparently there have have quite a large number of them.
I contend that this is "proof" that mercury is the cause of these 5 diseases. Autism especially is going through legal court system for having injected mercury as a preservative in vaccines (thimerosal) It is a wonder to me, that health organizations and research firms have spent 50 years and kilograms of money on everything about Alzheimer, Parkinsons, Schizophrenia, Prion except looking for atoms of mercury inside of cells of diseased victims of these diseases.
Truly amazing that we spent 50 years and kilograms of money on these 5 diseases except for looking for atoms of mercury in the diseased body of victims of these diseases. And it takes a legal court battle over Thimerosal to get otherwise educated people to realize that a deadly poison of mercury is never safe no matter what the quantity of injection given.
I think every person with a degree in medicine who says mercury is safe should have their degrees annulled. I think the national health institutes in the USA who still tout the safety of thimerosal should have their degrees annulled as well as being lawsuited. For they abandoned science and logic long time ago.
When patients appear who have both Prion and Parkinsons concomitantly, or have Autism and Schizophrenia concomitantly or have Parkinsons and Alzheimers concomitantly, signifies the proof evidence that one chemical poison is behind these 5 diseases.
I would send all the doctors at NIH who ever spoke kindly of Thimerosal, packing back to school and learn some logic.
Archimedes Plutonium www.iw.net/~a_plutonium whole entire Universe is just one big atom where dots of the electron-dot-cloud are galaxies
plutonium.archimedes@gmail.com - 11 Aug 2008 21:13 GMT Now I was looking today for a website that describes a patient who has Autism and has simultaneously the "early onset Alzheimer's". I found no names of a person who has both autism and early onset Alzheimer's although some websites "hint" of there being such cases.
I did find this website:
http://townmusician.blogspot.com/2008/03/alzheimers-autism-connection.html
Saturday, March 08, 2008 Birgit Calhoun
--- quoting a paragraph of that blogspot --- The good version contains the most sulfur. The bad version doesn't contain any. It is known that mercury loves sulfur.
Autism and Alzheimer's might be caused by mercury poisoning. Carrying the thought a little further, it is known that those ApoEnzymes are the only enzymes that can transport mercury out of the brain so it can be excreted. --- end quoting that blogspot ---
I quoted that because it harmonizes with my recent statement of how mercury as the solo cause of all 5 diseases, how the mercury can cause these 5 diseases depending on the stage of life the victim is in. If a person is 2 years old and gets a dose of mercury, then it translates into Autism. If a person is a teenager and gets a dose of mercury, it is not Autism that results but Schizophrenia. If a person is in 50's and gets a dose of mercury the result is not Autism nor Schizophrenia but Parkinsons. All the way up to Alzheimers.
So in the above paragraph we can see how doses of mercury at various stages of life of a person can bring forth one of those 5 diseases.
So when I want to picture a mechanism of how solo mercury can cause 5 diseases in the developing brain from birth to age 70's, it is a mechanism of mercury tearing out sulfur and the brain unable to remove that mercury because the mercury destroys the removal-proteins. And there is a link between the developing regions of the brain. In infancy, mercury would destroy the speech centers. In teenager years the mercury would destroy neocortex connections and result in schizophrenia.
In old age, the mercury would attack either one of these three centers--- Parkinson, CJD or Alzheimer.
In medicine, up to this moment, we viewed those three diseases as different and distinct. But with mercury as the solo cause, we can say that Parkinson is a form of Alzheimer and that Prion disease is a form of Alzheimers. In old age, where the mercury attacks the brain is any number of sites all leading to deformation of proteins. Does it matter if the mercury deforms beta amyloid or tau or alpha synuclein or Lewy bodies or prion proteins? No, it really does not matter because it is all due to the presence of mercury in the brain causing the deformations.
The medical literature is swamped by reports of genetic causes. This is a pitiful shame, since these five diseases are not genetically caused. If the world had no mercury entering human bodies, none of these 5 diseases would exist. The genetic influence is that families usually have a higher risk of eating mercury fish or mercury vaccines or mercury tooth fillings or breathing coal fired mercury air near their homes. Plus a family is likely to have the same body reaction to the ingested or inhaled mercury.
So medicine has to begin to revert this massive misguided "genetic basis" for these 5 diseases. It is not genetics. It is mercury poisoning. Instead of wasting another 50 years and money on genetic research we must now begin to apply chemical analysis of mercury in brain tissue and brain cells. Instead of millions of reports to journals on some genetics of these 5 diseases we need reports of mass spectroscopy on mercury atoms inside of cells of the brain.
Archimedes Plutonium www.iw.net/~a_plutonium whole entire Universe is just one big atom where dots of the electron-dot-cloud are galaxies
Archimedes Plutonium - 12 Aug 2008 09:45 GMT What is going on with sci.med that Google does not recognize it?
Here is a website of an abstract from Japan of a woman who had both Parkinson and Prion diseases simultaneously.
http://www3.interscience.wiley.com/journal/118980175/abstract?CRETRY=1&SRETRY=0
As I noted earlier, if mercury is the root cause of these 5 diseases then slowly but surely we should see cases of where victims of two or more of these diseases simultaneously. The most prevalent ones should be where the transition ages are close together so that a dosage of mercury would start the onset of two nearby-aged diseases such as Parkinson's and Prion, or Prion and Alzheimers.
The most difficult concomitant cases would be Autism simultaneously Alzheimers. It is more likely for Autism simultaneous with Parkinsons or especially Autism simultaneously with Schizophrenia.
Archimedes Plutonium www.iw.net/~a_plutonium whole entire Universe is just one big atom where dots of the electron-dot-cloud are galaxies
|
|
|