 |
 | Home | Contact Us | FAQ | Search & Site Map | Link to Us |
 | Sign In | Join | Other 45 Sites in Network |
Natural Science Forum / Biology / Biology / August 2008#71 beginning to explain why there is beta-amyloid and tau-protein in Alzheimer's ; new book: Metal Causation coupled with Weak-Protein-Point ^Theory of Medicine: Autism, Schizophrenia, Parkinson's, Prion, Alzheimer's
First I used the keywords of sulfur beta amyloid tau sulfur Alzheimer and then I changed the word sulfur to that of "sulphur" If MERCURY is the solo cause of these 5 diseases, it should explain why there are two proteins involved in Alzheimers. The explanation, I feel is probably due to the idea that mercury loves sulfur and deforms molecules in the brain that have sulfur atoms. Previously, I thought the pathology involved mercury deforming other metal ions due to a "amalgam force". I abandon that mechanism, realizing that the ability of mercury to scavenge sulfur atoms and deform molecules containing sulfur is the primary mechanism. So why is there two proteins gone awry in Alzheimer's. I focus on the last listed hit below: --- quoting several hits from Google --- Specific saccharide compositions and methods for treating ... 424/709 , Sulfate 424/78.35 , Nitrogen or sulfur containing monomer 514/23 ... "Amyloid Plaque Core Protein in Alzheimer Disease and Down Syndrome," Proc. ... www.patentstorm.us/patents/6037327.html - Similar pages - Note this by G Castillo - 2000 - Cited by 3 - Related articles - All 7 versions Methods for using specific saccharides for treating alzheimer's ... “Amyloid Plaque Core Protein in Alzheimer Disease and Down Syndrome,” Proc. Natl. Acad. Sci. ... saccharide radical containing) DOAI536/118Sulfur containing ... www.patentstorm.us/patents/6767898.html - Similar pages - Note this by AD Snow - 2004 - Related articles - All 4 versions More results from www.patentstorm.us » Medical Hypotheses : Oxidant free radical initiated chain ... Selenium, sulfur amino acids and vitamin C provide reducing conditions. ... Specifically, Alzheimer's disease is characterized by tau protein tangles in the ... linkinghub.elsevier.com/retrieve/pii/S0306987704001100 - Similar pages - Note this by A Tappel - 2004 - Cited by 2 - Related articles - All 3 versions Why is the amyloid beta peptide of Alzheimer’s disease neurotoxic? to Ab. We showed computationally that the resulting sulfur radical ..... 31 R. Bhatia, H. Lin and R. Lal, Fresh and globular amyloid beta protein ... www.rsc.org/ej/DT/2008/b718601k.pdf - Similar pages - Note this by A Rauk - 2008 - Related articles - All 2 versions Molecular Psychiatry - Validation of amyloid-[beta] peptides in ... by metal ions at met-35 produces a sulfuramyl free radical on the sulfur atom.43 .... Tau protein, beta-amyloid (1-42) and S100B protein in cerebrospinal ... www.nature.com/mp/journal/v12/n7/full/4001967a.html - Similar pages - Note this by M Bibl - 2007 - Cited by 6 - Related articles - All 4 versions NOW REPLACING sulfur with sulphur CSF amyloid-{beta}-peptides in Alzheimer's disease, dementia with ... -helical structure alters the electronic environment around the sulphur of ..... Tau protein, beta-amyloid (1-42) and S100B protein in cerebrospinal fluid ... brain.oxfordjournals.org/cgi/content/full/129/5/1177 - Similar pages - Note this by M Bibl - 2006 - Cited by 24 - Related articles - All 5 versions (WO/2007/145589) PEPTIDES THAT ARE CAPABLE OF BINDING TO AMYLOID ... Hoshi, M., et al., Spherical aggregates of beta-amyloid (amylospheroid) show high neurotoxicity and activate tau protein kinase I/glycogen synthase ... www.wipo.int/pctdb/en/wo.jsp?IA=WO2007145589&WO=2007145589&DISPLAY=DESC - 39k - Cached - Similar pages - Note this Elevated glutathione as a therapeutic strategy in Alzheimer's disease Olney JW, Ho O, Rhee V. 1971. cytotoxic effect of acid and sulphur ... regulates beta-amyloid precursor protein gene transcription in ... doi.wiley.com/10.1002/ddr.10095 - Similar pages - Note this by DA Butterfield - 2002 - Cited by 23 - Related articles - All 2 versions 1-[Alkyl], 1-[(heteroaryl)alkyl] and 1-[(aryl)alkyl]-7-pyridin-4 ... It was later recognized that GSK3 beta was identical to tau protein kinase 1 (TPK1), ... when Y represents an oxygen atom, a sulphur atom, a sulfonyl group, ... www.freepatentsonline.com/EP1184385.html - Similar pages - Note this --- end quoting several hits from Google --- Apparently the reason Alzheimer's involves two proteins of beta amyloid and tau protein is that both involve sulfur (or to the British, sulphur). Mercury reacts the same with molecules that contain sulfur. In a sense, the fact that both tau-protein and beta-amyloid are involved in Alzheimer's is a *Proof* that mercury is the underlying cause of Alzheimer's. In the other 5 diseases we have multiple proteins involved. In Parkinson's we have a plethora of proteins other than alpha synuclein. In Prion, we have a plethora of deformations of prion-protein, simply called variants. Why multiple proteins? Because they all have the same thing in common, multiple sites of sulfur atoms in the molecules that mercury attacks. Archimedes Plutonium www.iw.net/~a_plutonium whole entire Universe is just one big atom where dots of the electron-dot-cloud are galaxies (snipped) > If MERCURY is the solo cause of these 5 diseases, it should explain > why there are two proteins involved in Alzheimers. The explanation, [quoted text clipped - 5 lines] > that the ability of mercury to scavenge sulfur atoms and deform > molecules containing sulfur is the primary mechanism. I have two pictures of how mercury atoms cause these 5 diseases. First, I can picture where the mercury-compound (ethyl-mercury or methyl-mercury or some other compound of mercury) is like a catalyst that comes in contact with molecules in the brain and deforms the molecule especially at sites of sulfur atoms. So in this picture, I can see mercury as a catalyst that remains unchanged itself but causing deformations in the molecules it contacts. Second, I can picture mercury as becoming bound with molecules in the brain and deforming them such as a mutation in the synthesis of proteins and thus generating the disease. In Prion disease, I envision the pathology as where mercury acts like a catalyst. Also in Alzheimers where mercury as a catalyst can pretty well explain why it takes 10 or more years for the disease to unfold as it slowly deforms more and more proteins in the path of the mercury catalyst. In Autism, the actions of mercury seem to be of a bound-mercury at a development site where nerves are formed. Unlike a wandering catalyst of mercury that deforms contacted proteins, in Autism the mercury seems to stay put at a synthesis sequencing site and halts the formation of nerves. Now whether the male and female hormones plays a huge role in whether Autism occurrs is a matter to be researched. I think it plays a major role in why 75% of Autism is boys. The female hormone must be capable of removal of mercury excess much easier than the male hormones of an early age. In Parkinson's, apparently the mercury must be like Autism where it latches to a site of the brain and causes a deformation in the Synthesis Sequencing. Archimedes Plutonium www.iw.net/~a_plutonium whole entire Universe is just one big atom where dots of the electron-dot-cloud are galaxies plutonium.archime...@gmail.com wrote: > (snipped) > > > > If MERCURY is the solo cause of these 5 diseases, it should explain > > why there are two proteins involved in Alzheimers. The explanation, > > I feel is probably due to the idea that mercury loves sulfur and > > deforms molecules in the brain that have sulfur atoms. I should start some form of NOTEBOOK of notes on sulfur and mercury inside of cells. So let me start this notebook: (1) I probably cannot get away with this statement "all proteins have at least a sulfur atom attached" I probably am correct when saying that 99% of protein molecules have a sulfur atom attached (2) The sulfur atom attached to a protein has hydrogen atoms attached to the sulfur but when mercury atoms come in contact, the hydrogen is emitted (3) When mercury binds with the sulfur atom on a protein, it can bind with several protein sulfur atoms depending if the mercury is divalent. (4) Mercury will always deform the shape and thus the function of the protein once it binds and once the mercury leaves the protein. (5) Mercury can act as a catalyst amoung protein molecules. (6) Proteins are made from first a Messenger RNA. (7) Messenger RNA goes to the cytoplasm of the cell to begin to make proteins (8) In the cytoplasm is Ribosomal RNA (9) the Messenger RNA links with the Ribosomal RNA reading the message and producing the new protein (10) sulfur atoms exist in all the Messenger RNA and the Ribosomal RNA (11) thus, if mercury comes in contact with Messenger RNA or Ribosomal RNA could instantly cause the creation of rogue proteins (12) Cells of the human body are actually two cells in one, where mitochrondria-- the source of energy of cells are actually independent bodies. So that Mitochondria, in a sense, are smaller cells inside of larger cells. (13) the number of mitochrondria in muscle cells can number in the thousands. I need to find out a typical upper bound of mitochrondria (14) Every mitochrondria has sulfur atoms (15) None of the proteins associated with the 5 diseases is a protein of the mitochrondria (16) All the proteins associated with the 5 diseases are proteins of the regular cell and were created in the cytoplasm of the regular-cell Comments: From those notes, I can begin to visualize where mercury acts as a catalyst and runs around creating deformed proteins such as in Prion or Alzheimer's disease or in Parkinson's disease. Also, the above gives me a window into how mercury in a infant can get into the cytoplasm of an infants brain and reside and lodge in the Messenger RNA and Ribosomal RNA and cause for there to be the lack of formation of nerve-endings and thus create Autism. Not sure yet why boys have 75% of Autism with girls 25%. Perhaps the sex hormone causes girls to excrete the mercury rather than lodge in the RNA. Archimedes Plutonium www.iw.net/~a_plutonium whole entire Universe is just one big atom where dots of the electron-dot-cloud are galaxies |
Reply to this Message |
 Sign In
 Join
 My Latest Posts My Monitored Threads My Blog My Photo Gallery My Profile My Homepage Start New Thread Enable EMail Alerts Rate this Thread
|
©2009 Advenet LLC Privacy Policy - Terms of Use
This website includes both content owned or controlled by Advenet as well as content owned or controlled by third parties.