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Natural Science Forum / Biology / Biology / April 2007new book: Metal Causation coupled with Weak-Protein-Point ^Theory of Medicine (Autism, Alzheimers, Parkinsons, Schizophrenia, Prion)
New book: "Metal Causation coupled with Weak-Protein-Point ^Theory of Medicine (Autism, Alzheimers, Parkinsons, Schizophrenia, Prion)", Archimedes Plutonium, Internet book published 1995??-2007 (assimilated in April 2007 in sci.med,sci.chem,sci.bio.misc) Preface: For Medical Science: The Metal Causation coupled with Weak-Protein- Point in the body when foreign metals are present. These 5 family-related-diseases of Alzheimers, Parkinsons, Prion, Autism, Schizophrenia are mostly caused by foreign mercury in the body in conjunction with other metals such as cesium and rubidium and silver. When the body has these foreign metals, they wreck havoc on proteins and protein synthesis and start the disease. We need a new tool of Mass Spectroscopy of disease tissue to find out exactly what metals and the amount of metals that cause these 5 diseases. So many of the TV news hours are covering this epidemic disease of autism and so I want to get this book out there in public view as fast as possible. I have been working on these five diseases for over a decade, having started this research with Prion disease approximately 1995 (will find out accurate date later). Anyway, all these 5 diseases appear to lie in the brain region of the body. Most of them appear to be modern day diseases and lesser known in ancient times. The frequency of catching any one of these 5 diseases seems to be on the rise in our modern times. This has led me to the idea that the culprit or causation of these 5 diseases is metal contamination in the environment and especially the toxic metal of mercury. Autism is a childhood disease, and our environment has a heightened prescence of mercury due to vaccination of babies with a mercury component in the shots administered or the drugs administered to babies. And to the prevalence of coal fired power stations that emit mercury into the air we breathe. To the common prevalence of mercury in switches and gadgets in the household. The geography of where these 5 diseases occur most often is where there are a density of coal fired power stations. The state of Utah in the USA, and the country of Great Britian are prime examples of mercury concentrations. When I started this research circa 1995, I started with Prion disease and the fact that Papua, New Guinea had the prion disease called Kuru on the rise because of cannibilistic rituals of eating the brains. And it was later hypothesized that a rogue-protein is the cause of this disease of prion or CJD. But is it really a protein or could it have been the case that the New Guinea tribe injested or imbibed mercury, for there is alot of coal mining in New Guinea and perhaps thermometers filled with mercury had accidentally entered their food supply. This new theory of medicine contends that what causes these 5 diseases is that a toxic metal such as mercury enters the body and goes to the brain region where the weakest protein synthesis is damaged by the presence of this toxic metal or combinations of toxic metals such as rubidium and cesium and mercury and lead. The youngest and oldest would be most vulnerable to toxic metal causing protein synthesis to go awry. So in the case of Autism, just a tiny bit of mercury in the body would mess up a protein synthesis site in the brain and that child will forever be not normal. Just a tiny bit of mercury can spoil an entire life. In the case of Alzheimers and Parkinsons, the level of mercury builds up in the body and in old age, that level is enough to start Alzheimers and Parkinsons. In middle age these diseases are not common because the body is able to remove the toxic metals sufficiently. But as a case developed in the UK where young people caught CJD, it may be the case where a accidental spilling of mercury contaminated the food. In past history, mercury poisoning occurred often. But in our modern times, we are just beginning to see what the effect of low doses of mercury can wreck havoc on the health of many people. It is my belief that these 5 diseases are caused by the presence of low doses of toxic metals such as mercury. Archimedes Plutonium www.iw.net/~a_plutonium whole entire Universe is just one big atom where dots of the electron-dot-cloud are galaxies > New book: "Metal Causation coupled with Weak-Protein-Point ^Theory of > Medicine (Autism, Alzheimers, Parkinsons, Schizophrenia, Prion)", [quoted text clipped - 11 lines] > in conjunction with other > metals such as cesium and rubidium and silver. Prion diseases are caused by prions. Autism is not related to the other diseases. Rest of crap deleted. You have the wrong news groups. This has nothing to do with science. Jeff [usual junk] >You have the wrong news groups. This has nothing to do with science. > >Jeff Neither does Archie. New book: "Metal Causation coupled with Weak-Protein-Point ^Theory of Medicine (Autism, Alzheimers, Parkinsons, Schizophrenia, Prion)", Archimedes Plutonium, Internet book published 1996-2007 (assimilated in April 2007 in sci.med,sci.chem,sci.bio.misc) Chapters of this new book: (1) Preface (2) Introduction (3) Analogy disease of Asbestosis (4) Autism (5) Alzheimers (6) Parkinsons (7) Schizophrenia (8) Prion A few of the great features of writing and publishing a book on the Internet are these: (a) speed is maximized and there is no other book able to be published with this sort of speed, and it is like comparing a supercomputer of 2007 with that of primitive computer in the year 1957. (b) every idea has a date time group (c) revision is almost instantaneously allowed (d) outside feedback or comments or information is possible (e) the book can stay up to date, whereas all hardcover books have to suffer years of waiting to revise Archimedes Plutonium www.iw.net/~a_plutonium whole entire Universe is just one big atom where dots of the electron-dot-cloud are galaxies > New book: "Metal Causation coupled with Weak-Protein-Point ^Theory of > Medicine (Autism, Alzheimers, Parkinsons, Schizophrenia, Prion)", [quoted text clipped - 10 lines] > (7) Schizophrenia > (8) Prion Well this is kind of what I love about science, is that it is so compelling as to wanting to know that it takes precedence over wanting to organize. This book is about organizing my thoughts and research on this subject since 1996, but the opening pages catch me in leaping forward to the chapter on Prion diseases and the chapter on Autism. So I will try to stick to my goal of organizing and well-ordering of this book, but I seem to lapse into those occasions where my curiosity bolts me forward and out of place. Question: have researchers of Prion disease ever found a mercury atom as the center of the prion protein molecule? I know they find copper atoms as the center of the prion protein molecule, but have they ever found mercury? This is similar to the idea that a hemoglobin molecule has iron as its center. And, has any researcher placed mercury compounds in a solution of prion protein molecules and observed what happened, and not forgetting to add a current to the solution to simulate the brain currents. One must keep in mind that all the above diseases are brain diseases and the brain is the part of the body that is ELECTRICAL. This electricity of the brain is the major factor why these diseases occurr in the first place. Autism: as to autism the Japanese mercury tragedy of Minamata involved methylmercury. The Thimerosal preservative for vaccines to babies is almost 50% ethylmercury. The symptoms of Autism through its broad spectrum of symptoms closely matches the symptoms of mercury poisoning. Question: has anyone conducted a survey of families where an autistic child is born and whether the mother had alot of Tuna fish or other seafood in her diet up to the pregnancy and up to the birth of her child? Anyway, I was avidly looking for research on the myelin sheaths of brain nerves for it is the Myelin Sheaths that is attacked by mercury poisoning. And looking for the location of the brain of babies where autism would take hold by not forming adequate Myelin Sheaths of Brain cells. I am trying to locate the part of the brain that is so to speak "dissolved by mercury prescence" so that brain sheaths cannot form. And this region of the brain would cause the Autistic antisocial behaviour. I could not find anything in the Autism research as to a location of damaged brain cells for autism. What I am trying to link is the known fact that mercury prevents the formation of nerve sheaths. If I can show that autism is the lack of development of a mass of nerve sheaths, then I have linked Autism to Mercury poisoning. So, I know as a solid fact that mercury prevents the formation of Nerve Sheaths. So all I have to show now, is that Autism is the lack of development of some specific nerve sheaths. If I can do that, then I will have shown that Autism is in fact mercury poisoning. Now there is a huge range or spectrum of Autism, and to me that means there is a huge range of what kind of mercury compound and the dosage of the mercury compound and when the infant had contact with that mercury compound. Now there was a very silly report out of Israel about Autism connected to older men. This is silly because it is statistical and the explanation could well be something as simple as the fact that older men were able to get free medical care and required to get Thimerosal shots for their infants. Or it could be the case that families with older men ate twice as much tuna fish. So this older men hypothesis is really bad science for it is easily explained away. Archimedes Plutonium www.iw.net/~a_plutonium whole entire Universe is just one big atom where dots of the electron-dot-cloud are galaxies New book: "Metal Causation coupled with Weak-Protein-Point ^Theory of Medicine (Autism, Alzheimers, Parkinsons, Schizophrenia, Prion)", Archimedes Plutonium, Internet book published 1996-2007 (assimilated in April 2007 in sci.med,sci.chem,sci.bio.misc) Chapters of this new book: (1) Preface & Introduction (2) Analogy disease of Asbestosis (3) Autism (4) Alzheimers (5) Parkinsons (6) Schizophrenia (7) Prion This is a beautiful book and a change of pace for me as my last several books have been monograph-books. Monographs are shortened books and focused on a specific topic and of 100 pages or less. A full book is long and expansive and tends to be general and not so specific. In this book I will cover 5 well known diseases that are afflicting modern society and this book gives a new theory about all these five diseases. It is a new theory because a disease was never considered to be a overdose of some natural material. In the case of the 5 diseases, the most common culprit is mercury, but in the case of say schizophrenia it maybe a combination of silver and mercury or in the case of prion disease a combination of copper and mercury or even cesium and rubidium, or in the case of Parkinsons, a combination of mercury and some other element. The fundamental idea is that the brain is an electrical environment which does something to mercury and other elements that are foreign to the brain and wrecks havoc on the brain. And because these foreign elements are in the brain which should not be, that at a high enough dosage, there is a breakdown of a weakpoint in the brain to these foreign metals. For Autism it is the lack of nerve sheaths; for Parkinsons the weak point is alpha synuclein; for Alzheimers the weak point is beta amyloids; for Prion it is prion proteins. So the basic idea is that when the brain has too much of a metal, there is a weakpoint that is damaged. Once damaged the disease has started. Now some consider the above 5 diseases as genetic or partly genetic. That is not true for these diseases are all environmental. Because mercury overdose is an environment issue. And the very best way to talk about these 5 diseases is to make the ANALOGY to a another environment disease that is well known-- Asbestosis. So Autism, and Alzheimers and Parkinsons and Schizophrenia, and Prion are diseases very much like Asbestosis only the toxic agent is not a asbestos fiber but a overdose of mercury and other metals that reach the brain. Once these toxic metals reach the brain and are in an overdose capacity, they wreck havoc on a weak-point of the brain and thus start the individual disease. In the case of Alzheimers and Parkinsons and Prion CJD are most often old age diseases and this is because at a certain age our body can no longer dismiss the mercury buildup of all those years. Remember that the young body removes metals, but that the older and aging body loses its ability to remove foreign metals from the brain. So the onset of Alzheimers is most often in old age. And one could say that Alzheimers is the Autism of old age or the other way of saying that Autism is a infant that has caught Alzheimers. Both involve mercury destruction of part of the brain. And I would like to challenge the science medical community to statistically research the numbers of Autism and Alzheimers as per geography with coal fired power stations and the eating of Tuna fish and other fish. In other words the geography where there is alot of mercury in the environment is the place where the highest rates of both Autism and Alzheimers occurs. It is nice getting back to writing a full length book, but I am going to make it easy on myself because I am going to refer to the thousands and thousands of past posts to the science newsgroups on these 5 diseases that I have been discussing with many other scientists since 1996. There were many dead-ends in the discussion and many time wasting excursions, such as for example when I started this discussion in 1996 I thought prion disease was really caused by fungus, analogy to the ant that is killed and brain parasitized by fungus. But that massive discussion starting in 1996 was all fruitful since it culminated in this theory that includes 5 major diseases. The key to this book and theory is that I picked a beautiful analogy of Asbestosis, which I will compare with each of these 5 diseases. In the future of humanity will arise new diseases, here to for unknown, because these new diseases will be an overdose of some metal which we do not have now. Perhaps some element which we have little use now will be prevalent in the environment and this will lead to a new disease when in overdose in our body. So the key to this book is the analogy to Asbestosis. And the idea of this book is that the brain is a special environment of electrical pulses and for which too much mercury or other foreign metals will attack a weak point of the brain and cause to arise one of the 5 diseases listed. Archimedes Plutonium www.iw.net/~a_plutonium whole entire Universe is just one big atom where dots of the electron-dot-cloud are galaxies In science, to make a theory clear it is best to find a analogy that sews it all together. In the case of these 5 diseases: Autism, Alzheimers, Parkinsons, Schizophrenia and Prion there is an analogy disease known as Asbestosis. So let me talk about Asbestosis and then relate these 5 diseases to Asbestosis. Instead of asbestos fibers causing asbestosis, it is mercury and other toxic metals that cause the 5 above diseases but it is the analogy which exlpains the Weak-Protein-Point best. When asbestos fibers get into the body, they are almost impossible to remove, and the damage they cause is because they are almost impossible for the body to remove plus the fact that some of these fibers act like tiny pinheads or knives that poke or cut a cell or molecule and in the poking or cutting forms a cancer. So once asbestos gets into the body, it is almost impossible to remove and then it cuts or pokes and causes damage to molecules which in turn increases cancer rates. Theoretically, just one asbestos fiber can lead to a cancer. Theoretically, then, applying the analogy, just one atom of mercury in conjunction with other toxic metals could lead to Autism, Alzheimers, Parkinsons, Schizophrenia, or Prion. In Practice though, Prion disease suggests more than 10 units of the causative agent starts the onset of the disease. I remember reading some source in the 1990s that suggested a quantity of more than 10 units to begin the Prion disease. The mechanism in Asbestosis is that the body immune system mounts an attack on the foreign asbestos fibers and thus fills up the space of the lungs to where the lungs cannot breathe properly. Or, the fibers cut or poke holes into the surrounding molecules which brings on a cancer. Now compare that mechanism to the mechanism for each of the 5 diseases. I shall do that in each of the individual chapters of these 5 diseases but overall want to discuss the mechanism now. All 5 diseases have a abnormality associated with some protein or protein synthesis. Mercury is a compound in several forms such as ethylmercury, methylmercury, dimethylmercury etc etc. And mercury in conjunction with other metals such as copper, silver, rubidium, cesium, aluminum can cause a spectrum of a disease such as Autism has numerous varieties of Autism and Prion has numerous varieties of Prion disease. Asbestos, likewise can cause a variety of cancers, if the asbestos fiber is in the stomach then a stomach cancer ensues or if in the lungs a lung cancer ensues. But the mechanism of Autism, Alzheimers, Parkinsons, Schizophrenia, and Prion is where a toxic metal/s enter the body and end up in the brain which is a electrical environment and the electricity of the brain plays a major role. These toxic metals end up in the brain and depending on the age of the person and where these metals end up in a specific region of the brain, then damage the protein synthesis of that brain region. So that in the case of Autism, a protein synthesis site is irrevocably damaged that the disease ensues. All 5 of these diseases like asbestos is relatively new to humanity because the prevalence of asbestos and mercury (other toxic metals) is a modern day phenomenon where it is so widespread in the environment which it was not in the historical past. We have ample mercury in the air we breathe due to coal fired power stations and even the food we eat such as tuna-fish. We have ample contact with silver metal which is implicated in Schizophrenia. We have ample contact with cesium and rubidium due to the coal fired power stations which is implicated in Prion diseases. All 5 diseases have some protein misfunction and mercury and other toxic metals can destroy protein synthesis sites. Analogously, asbestos fibers can cut or poke a hole into a molecule which ends up as cancer. All 5 diseases involve proteins and all are located in the brain where electricity plays a major role. All 5 except Autism are mostly old age diseases and that indicates either a sufficient quantity of toxic metal buildup or the body can no longer remove the metals. Archimedes Plutonium www.iw.net/~a_plutonium whole entire Universe is just one big atom where dots of the electron-dot-cloud are galaxies Now in Asbestosis fiber masses buildup in the lungs as the immune system tries to remove the asbestos and causing shortness of breathe. Now in Alzheimers and Prion there is a fiber buildup of proteins which in turn becomes a fibrous mass and leading to death. But that is the immune response of the body trying to get rid of the foreign asbestos fiber which is resistant to being removed. But the other danger of asbestos is the poking and cutting by the sharp fibers can lead to the lung cancer or the mesothelioma cancer. Asbestosis was never a disease until modern times when it was mined and then put into commercial use where it was given wide presence and contact by many people. Just like Autism, Alzheimers, Parkinsons, Schizophrenia, Prion were modern day diseases because the toxic metals such as mercury were never so widespread use and prescence to most people. Every day we can be exposed to mercury by the air we breathe because of the coal fired electricity power stations emit mercury gases and by the tuna fish and other fish we happen to eat. To the preservative of vaccines administered to young babies or infants and thus increasing the chance of Autism. So this analogy is very excellent as we can replace asbestos fibers with that of toxic metals such as mercury. And we replace the mechanism of a immune response causing fiber buildup or poking and cutting by sharp asbestos with that of a mechanism of a weak point in the brain of protein synthesis that is damaged by toxic metal. And the geography where toxic mercury is abundant in the environment is a large group of people who have close proximity to coal fired power stations and who love eating alot of fish in their diets such as England and Western USA States. And in fact, one of the diseases listed as Prion traces its way back to Papua, New Guinea where not only is there mining present but that the mishandling of mercury would be a easy error. Maybe, even, some added mercury to the communal soup that was eaten. And in the case of Parkinsons, it was recently announced that bacteria in well-water is a likely culprit of this disease, considering that Parkinsons is concentrated in Farm land states where well water is usually the source of drinking water. But it is also known that bacteria filter mercury and that some bacteria have higher concentrations of mercury. Archimedes Plutonium www.iw.net/~a_plutonium whole entire Universe is just one big atom where dots of the electron-dot-cloud are galaxies Now the weakest point in the body for asbestosis is the lung region since the fiber mass buildup from the Immune System response debilitates the vital function of breathing, whereas if the asbestos buildup were to occur in another organ, the immune response would not be so harmful. So we can consider the lungs as the weakest point of the body for Asbestosis, but the stomach would also be a weak point but not as weak as the lungs. So now, transfer that analogy to mercury and other toxic metals into the brain region. Mercury comes in many forms such as dimethylmercury or methylmercury or ethylmercury and many other forms, and coupled with combinations of toxic metals such as mercury and cesium or mercury and rubidium or mercury and silver or mercury and copper just for examples. So that a combination of mercury and silver may start the onset of Schizophrenia in some specific region of the brain. A combination of mercury and rubidium may cause the onset of CJD (Prion). A specific type of mercury may be located in the brain where dopamine is utilized causing the onset of Parkinsons. And a specific type of mercury may attack the brain region where beta amyloid is synthesized leading to Alzheimers. A high quantity of mercury in an infant can destroy the ability of the brain to have nerve sheaths form for which the infant would grow up to be socially normal and thus stricken with Autism. So the analogy between Asbestosis and the region of weak-point for asbestos is the lung region but it could be the stomach and likewise for mercury and metal toxic material, the weakest point is the brain region where electricity environment plays a major role and where these metals then play havoc on a specific brain region. Now it used to be thought that several of these diseases of Autism, Alzheimers, Parkinsons, Schizophrenia, and Prion were hereditary or genetic in acquisition. But obviously Asbestosis is not genetic for the cause is a foreign material that gets into the body. Likewise, none of Autism, Alzheimers, Parkinsons, Schizophrenia or Prion is genetic in causation since the culprit is a foreign toxic metal/s. They may falsely have appeared as hereditary or genetic by cause since alot of individual cases occurred in families stricken by the disease. But when one family member is in close contact with say mercury, the likelihood is that all the family members are in close contact with mercury. I do not rule out genetics completely, because in the case of some of these diseases, a person and his/her family may have the genetics to remove mercury better than other people and so if mercury gets into their bodies, they have a better removal genetics to ward off the disease. Just as our analogy case of asbestosis, that perhaps some people, a few people, have genetics to where they are able to adequately remove the asbestos out of the body or to minimize the damage. Archimedes Plutonium www.iw.net/~a_plutonium whole entire Universe is just one big atom where dots of the electron-dot-cloud are galaxies New book: "Metal Causation coupled with Weak-Protein-Point ^Theory of Medicine (Autism, Alzheimers, Parkinsons, Schizophrenia, Prion)", Archimedes Plutonium, Internet book published 1996-2007 (assimilated in April 2007 in sci.med,sci.chem,sci.bio.misc) Chapters of this new book: (1) Preface & Introduction (2) Analogy disease of Asbestosis (3) Autism (4) Alzheimers (5) Parkinsons (6) Schizophrenia (7) Prion (8) how to medically prove the assertions of this book-- mass spectroscopy of brain tissue I need to add a chapter on how to prove the major claims of this book that these diseases are caused by toxic metals. And the best way to do that is a direct analysis of brain tissue for metals such as mercury and a mass spectroscopy is just the instrument to carry out that analysis. Just as chemistry has a neat procedure that can tell us if asbestos fibers are within a tissue, analogously, mass spectroscopy will prove or deny that toxic metals were present in the 5 diseases listed. Archimedes Plutonium www.iw.net/~a_plutonium whole entire Universe is just one big atom where dots of the electron-dot-cloud are galaxies > New book: "Metal Causation coupled with Weak-Protein-Point ^Theory of > Medicine (Autism, Alzheimers, Parkinsons, Schizophrenia, Prion)", [quoted text clipped - 11 lines] > (8) how to medically prove the assertions of this book-- mass > spectroscopy of brain tissue With each of these 5 diseases, I would like to list a protein molecule for which the synthesis of that molecule has gone awry in the brain. Where the electrical environment of the brain facilitates the gone awry synthesis and where mercury and other toxic metals causes this gone awry pathology. In the case of Autism I am sorry I cannot point to a protein or even point to a very specific region of the brain which can be called the site or location of Autism. Perhaps one of the reasons I cannot point to a location is because Autism is the missing of part of a normal brain. The nerve sheaths of the brain that makeup a normal person was destroyed by mercury and other toxic metals. So we have a disease where we have missing nerve sheaths and those sheaths have not be enumerated and cataloged. Where is the likely source of the mercury poisoning? A real good candidate is Thimerosal which is a mercury compound used in vaccines to preserve the vaccine and administered to young infants during much of the second half of the 20th century. But mercury is prevalent in the air we breathe due to coal fired electric power stations and prevalent in the food we eat such as tuna fish and other fish. Geography supports the assertion that mercury is involved in Autism by the fact that many cases of Autism are near coal fired power stations. Researchers of Autism need to find out what nerve sheaths are missing in Autism. Archimedes Plutonium www.iw.net/~a_plutonium whole entire Universe is just one big atom where dots of the electron-dot-cloud are galaxies New book: "Metal Causation coupled with Weak-Protein-Point ^Theory of Medicine (Autism, Alzheimers, Parkinsons, Schizophrenia, Prion)", Archimedes Plutonium, Internet book published 1996-2007 (assimilated in April 2007 in sci.med,sci.chem,sci.bio.misc) Now I want to rearrange the chapters of the specific 5 diseases in alphabetical order. Chapters of this new book: (1) Preface & Introduction (2) Analogy disease of Asbestosis (3) Alzheimers (4) Autism (5) Parkinsons (6) Prion (7) Schizophrenia (8) how to medically prove the assertions of this book-- mass spectroscopy of brain tissue And, what I would like to do is to make a Table for each of these 5 diseases so that as the years go by and I need to revise or update with latest new research findings that I simply replace lines of the table. So for the chapter on Alzheimers I start this table formatting: ALZHEIMER DISEASE Proteins gone awry involved -- beta amyloid Function of proteins gone awry -- Metals found in those proteins gone awry -- Site or Location of brain where this disease unfolds -- Pathology of disease -- Age of its victims -- Geography of disease prevalence -- Any mass spectroscopy of brain tissue of disease and what metals were found -- Any chemicals that may relieve the disease pathology -- So I want some uniform table for each of these 5 diseases of the important and assailant facts. Archimedes Plutonium www.iw.net/~a_plutonium whole entire Universe is just one big atom where dots of the electron-dot-cloud are galaxies > New book: "Metal Causation coupled with Weak-Protein-Point ^Theory of > Medicine (Alzheimers, Autism, Parkinsons, Prion, Schizophrenia)", [quoted text clipped - 26 lines] > > Proteins gone awry involved -- beta amyloid tau protein > Function of proteins gone awry -- > > Metals found in those proteins gone awry -- > > Site or Location of brain where this disease unfolds -- Temporoparietal Cortex > Pathology of disease -- buildup accumulation of those two proteins listed and no way of getting rid of them; a garbage dump effect When was the first reliably known case -- 1901 > Age of its victims -- starts in 70s and estimated that 80% of those over 85 contract the disease > Geography of disease prevalence -- industrialized and affluent countries, keeping age constant, have higher incidence > Any mass spectroscopy of brain tissue of disease and what metals were > found -- [quoted text clipped - 8 lines] > whole entire Universe is just one big atom > where dots of the electron-dot-cloud are galaxies > New book: "Metal Causation coupled with Weak-Protein-Point ^Theory of > Medicine (Alzheimers, Autism, Parkinsons, Prion, Schizophrenia)", > Archimedes Plutonium, Internet book published 1996-2007 (assimilated > in April 2007 in sci.med,sci.chem,sci.bio.misc) > Chapters of this new book: > (1) Preface & Introduction [quoted text clipped - 6 lines] > (8) how to medically prove the assertions of this book-- mass > spectroscopy of brain tissue Now I would like to get these diseases into a table-like format where it is easy to edit, and it focuses on what is important and the table- format is predictive of other diseases in that if we have similarities in one disease to the table of another disease implies these two diseases have common causality. I believe when these tables are completed that the five diseases listed have more in common than disparate. Perhaps if I put lines through each concept will enhance the tabular format. > ALZHEIMER DISEASE --------------------------------------------------------------------- > Proteins gone awry involved -- beta amyloid tau protein -------------------------------------------------------------------- > Function of proteins gone awry -- -------------------------------------------------------------------- > Metals found in those proteins gone awry -- -------------------------------------------------------------------- > Site or Location of brain where this disease unfolds -- Temporoparietal Cortex -------------------------------------------------------------------- > Pathology of disease -- buildup accumulation of those two proteins listed and no way of getting rid of them; a garbage dump effect --------------------------------------------------------------------- When was the first reliably known case -- 1901 --------------------------------------------------------------------- > Age of its victims -- most commonly starts in 70s and estimated that 80% of those over 85 contract the disease --------------------------------------------------------------------- > Geography of disease prevalence -- industrialized and affluent countries, keeping age constant, have higher incidence ---------------------------------------------------------------------- > Any mass spectroscopy of brain tissue of disease and what metals were > found -- ----------------------------------------------------------------------- > Any chemicals that may relieve the disease pathology -- ----------------------------------------------------------------------- Archimedes Plutonium www.iw.net/~a_plutonium whole entire Universe is just one big atom where dots of the electron-dot-cloud are galaxies > ALZHEIMER DISEASE --------------------------------------------------------------------- > Proteins gone awry involved -- beta amyloid and tau protein -------------------------------------------------------------------- > Function of proteins gone awry -- -------------------------------------------------------------------- > Metals found in those proteins gone awry -- -------------------------------------------------------------------- > Site or Location of brain where this disease unfolds -- Temporoparietal Cortex -------------------------------------------------------------------- > Pathology of disease -- Buildup accumulation of those two proteins listed and no way of getting rid of them; a garbage dump effect. This is what I wrote in January of 2004 --- Newsgroups: sci.med, sci.chem, sci.bio.technology From: a_pluton...@hotmail.com (Archimedes Plutonium) Date: 26 Jan 2004 22:56:23 -0800 Local: Tues, Jan 27 2004 1:56 am Subject: how the APP Scissors becomes rogue and whether magnetic- manganese or fluorine is to blame?? I am still pondering how the APP scissors in Alzheimers makes two cuts of above and a tinier fragment below in which this tiny fragment is beta amyloid and wanders off to congregate into plaque. I am wondering if the MagneticManganese is the cause of this normal Scissors turning into a rogue scissors and thus the fundamental cause of Alzheimers disease? So does the MagneticManganese get into the Chromosome #21 where Downs Syndrome starts and where fast-acting hereditary Alzheimers starts? Does the MagneticManganese enter into the Chromosome 21 and thus cause the creation of faulty rogue scissors? Or does the MagneticManganese alter the scissors after Chromosome #21 has created partially rogue scissors. --- --------------------------------------------------------------------- When was the first reliably known case -- 1901 --------------------------------------------------------------------- > Age of its victims -- most commonly starts in 70s and estimated that 80% of those over 85 contract the disease --------------------------------------------------------------------- > Geography of disease prevalence -- quoting from this website: http://www.cdc.gov/mmwr/preview/mmwrhtml/00001820.htm "In 1987, age-adjusted death rates were highest in the Rocky Mountain states and in New England (Table 2). Montana and Utah had the highest rates in 1987 and the greatest differences in rates between 1979 and 1987. New York and Alaska had the lowest rates in 1987 and the smallest differences in rates between 1979 and 1987." The state of Utah, sorry to say, has one of the highest exposure to mercury from the mining and wind blown over Nevada mercury mining. Sorry to say that Utah fares badly in concentration of these five diseases and the thesis of this book is that mercury is the main causation. ---------------------------------------------------------------------- > Any mass spectroscopy of brain tissue of disease and what metals were > found -- ----------------------------------------------------------------------- > Any chemicals that may relieve the disease pathology -- ----------------------------------------------------------------------- Toxic metals that are hypothesized by AP as the root cause: I believe it is mercury in combination with perhaps other toxic metals. I believe mercury for old people is the reverse of mercury for babies in that mercury in babies leads to Autism and mercury in old people leads to Alzheimers. ----------------------------------------------------------------------- Archimedes Plutonium www.iw.net/~a_plutonium whole entire Universe is just one big atom where dots of the electron-dot-cloud are galaxies AUTISM DISEASE --------------------------------------------------------------------- (1) Proteins gone awry involved -- Missing nerves and nerve sheaths. -------------------------------------------------------------------- (2) Function of proteins gone awry -- Allows electrical communication which allows for normal socialization of a human being. -------------------------------------------------------------------- (3) Metals found in those proteins gone awry -- -------------------------------------------------------------------- (4) Site or Location of brain where this disease unfolds -- Lack of neurons and neuron sheaths in amygdala. -------------------------------------------------------------------- (5) Pathology of disease -- Mercury poisoning prevents nerves and nerve sheaths from forming. So in Autism, there are nerves and nerve sheaths missing. --------------------------------------------------------------------- (6) When was the first reliably known case -- --------------------------------------------------------------------- (7) Statistical incidences of Autism in the general USA population -- About 40 cases per 6,000 population. --------------------------------------------------------------------- (8) Age of its victims -- >From birth to around 7 years old, depending on the dose of mercury contact. --------------------------------------------------------------------- (9) Geography of disease prevalence -- A study done in Texas gives this information. Quoting from this website: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt= AbstractPlus&list_uids=16338635 "There was a significant increase in the rates of special education students and autism rates associated with increases in environmentally released mercury. On average, for each 1,000 lb of environmentally released mercury, there was a 43% increase in the rate of special education services and a 61% increase in the rate of autism." ---------------------------------------------------------------------- (10) Any mass spectroscopy of brain tissue of disease and what metals were found -- ----------------------------------------------------------------------- (11) Any chemicals that may relieve the disease pathology -- ----------------------------------------------------------------------- (12) Toxic metals that are hypothesized by AP as the root cause: I believe it is mercury, some organic mercury compound. I believe mercury for old people is the reverse of mercury for babies in that mercury in babies leads to Autism and mercury in old people leads to Alzheimers. ----------------------------------------------------------------------- Archimedes Plutonium www.iw.net/~a_plutonium whole entire Universe is just one big atom where dots of the electron-dot-cloud are galaxies Alright, one of the purposes of drawing tables for these five diseases is to make more easy correlations and connections between these diseases. So let me begin with correlating the pathology of Alzheimer with that of Autism keeping in mind that mercury is the alleged cause of these diseases. First thing I need to do is see where the site of the disease occurs in Alzheimer and Autism which means I have to find out where the Temporoparietal Cortex and the Amygdala are, respectively. So I need a website which has a brain map I found this site helpful: http://www.bbc.co.uk/science/humanbody/body/interactives/organs/brainmap/ And quoting this interesting piece of the brain: "Fornix this is a pathway of nerve fibres that transmits information around the limbic system" I need to correlate the Alzheimer pathology with the Autism pathology: I am still pondering how the APP scissors in Alzheimers makes two cuts of above and a tinier fragment below in which this tiny fragment is beta amyloid and wanders off to congregate into plaque. I am wondering if mercury compound can cause this normal Scissors turning into a rogue scissors and thus the fundamental cause of Alzheimers disease? So does mercury get into the Chromosome #21 where Downs Syndrome starts and where fast-acting hereditary Alzheimers starts? Does mercury enter into the Chromosome 21 and thus cause the creation of faulty rogue scissors? Or does mercury alter Chromosome #21 altogether and thus is the cause of creating rogue scissors. Mercury poisoning prevents nerves and nerve sheaths from forming in Autism. So in Autism, there are nerves and nerve sheaths missing. Now I notice from that BBC picture map of the brain a pathway called the Fornix and is between the Temporoparietal Cortex and the Amygdala. So, now, if mercury is the cause of both Alzheimer and Autism and the location of both are nearby one another with the Fornix as the pathway between both, so that in young age of infant, mercury destroys the full formation of the Amygdala and Fornix, while in old age, mercury starts to fill up the Temporoparietal Cortex with garbage plaques that it cannot get rid of. I wish that BBC map was 3 dimensional so I could see it better. The CORRELATION between Alzheimer and Autism is that one of them miscuts proteins and leaves a beta amyloid fragment that accumulates into a plaque which the brain cannot get rid of whereas Autism mercury prevents nerves and nerve sheaths from forming. So one is a miscut and the other is a inhibitor. Perhaps at the young age of being born, mercury acts more as a inhibitory of the formation of a full brain, whereas in old age, mercury acts more as a mutator of proteins that forms the APP scissors so that the mutated scissors makes garbage proteins that accumulate. This mutator function sounds very much related to Prion disease where another protein accumulates as a garbage protein that the body cannot get rid of. So the correlation so far is that in Autism, mercury inhibits the full formation of a normal brain. In Alzheimer (and Prion) mercury mutates the protein synthesis such as the APP scissors which then causes garbage protein accumulation. Archimedes Plutonium www.iw.net/~a_plutonium whole entire Universe is just one big atom where dots of the electron-dot-cloud are galaxies > AUTISM DISEASE > [quoted text clipped - 37 lines] > > About 40 cases per 6,000 population. In some places as high as 1 case per 133 such as New Jersey, Georgia, Utah. > --------------------------------------------------------------------- > [quoted text clipped - 20 lines] > in the rate > of autism." Another study: http://www.environmentalintegrity.org/pubs/EIP%2050%20dirtiest%20news%20release% 20FINAL.pdf Which says: Plants in Texas, Pennsylvania, Alabama and Georgia ranked in top 50 plants, emitting 15 tons of mercury into the air, or 30% of all power plant mercury pollution. Which nicely explains why New Jersey, Georgia, Utah have the three highest rates when you consider the direction of wind. And for Utah which burns alot of coal and Nevada has alot of mercury mining. It would be interesting to see if Europe also has highest rates of autism linked with nearby coal-fired power stations. > ---------------------------------------------------------------------- > [quoted text clipped - 20 lines] > whole entire Universe is just one big atom > where dots of the electron-dot-cloud are galaxies PARKINSON DISEASE --------------------------------------------------------------------- (1) Proteins gone awry involved -- Alpha-synuclein Ubiquitin -------------------------------------------------------------------- (2) Function of proteins gone awry -- -------------------------------------------------------------------- (3) Metals found in those proteins gone awry -- -------------------------------------------------------------------- (4) Site or Location of brain where this disease unfolds -- Quoting Wikipedia on Parkinson: "decreased stimulation of the motor cortex by the basal ganglia, normally caused by the insufficient formation and action of dopamine" -------------------------------------------------------------------- (5) Pathology of disease -- Quoting Wikipedia on Parkinson: "The mechanism by which the brain cells in Parkinson's are lost may consist of an abnormal accumulation of the protein alpha- synuclein bound to ubiquitin in the damaged cells. The alpha-synuclein- ubiquitin complex cannot be directed to the proteosome. This protein accumulation forms proteinaceous cytoplasmic inclusions called Lewy bodies. Latest research on pathogenesis of disease has shown that the death of dopaminergic neurons by alpha-synuclein is due to a defect in the machinery that transports proteins between two major cellular organelles - the endoplasmic reticulum (ER) and the Golgi apparatus." --------------------------------------------------------------------- (6) When was the first reliably known case -- 1817 --------------------------------------------------------------------- (7) Statistical incidences of Parkinson's in the general population -- Approximately 20 per 100,000 in parts of USA. And as high as 1 in 100 aged over 65 in parts of China. --------------------------------------------------------------------- (8) Age of its victims -- Usually starts at age 57 - 60 --------------------------------------------------------------------- (9) Geography of disease prevalence -- Linked to farming and agriculture environment of mercury containing pesticides and fungicides. Linked also to well-water of mercury-eating-bacteria. Quoting from this site about bacteria involving mercury: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=187012 "The fate and impact of elemental mercury in closed bacterial cultures were examined. The quantity of elemental mercury oxidized by bacteria ranged from small amounts for Pseudomonas aeruginosa, P. fluorescens, Escherichia coli, and Citrobacter to essentially all of the added elemental mercury for Bacillus subtilis and B. megaterium." ---------------------------------------------------------------------- (10) Any mass spectroscopy of brain tissue of disease or of the hair of diseased victims and what metals were found -- ----------------------------------------------------------------------- (11) Any chemicals that may relieve the disease pathology -- ----------------------------------------------------------------------- (12) Toxic metals that are hypothesized by AP as the root cause: Organic mercury and possibly in conjunction with cadmium and lead ----------------------------------------------------------------------- Archimedes Plutonium www.iw.net/~a_plutonium whole entire Universe is just one big atom where dots of the electron-dot-cloud are galaxies The pattern was not obvious with just Alzheimer and Autism, but quite obvious now with a third disease of Parkinson. The pattern I speak of is that a toxic heavy metal such as mercury gets into the body and easily enters the brain where it destroys or alters the protein synthesis. This altered protein synthesis produces an unwanted protein such as beta amyloid in Alzheimer or alpha synuclein in Parkinson where it accumulates like a garbage dump leading to death. In Autism, the mercury prevents some nerves or nerve sheaths from forming to make a normal person. In Alzheimer and Parkinson, the mercury corrupts the protein synthesis creating roque proteins that kill the person. Mercury, like asbestos, is toxic to humans. And if you get enough mercury or asbestos in the body, it could easily lead to death. Now there are many forms of mercury, to mention just three-- methylmercury and ethylmercury and dimethylmercury. Each of which could lead to different diseases in different parts of the brain. And depending on what age of the person and depending on the dosage. But not only are there many types of organic and inorganic mercury, but there are also combinations of toxic metals that may cause different types of diseases and varieties of those specific diseases. There are many types of Parkinson disease. So the main thesis of this book is that mercury is a toxic metal and a small dose can bring on a brain disease which causes unwanted proteins to accumulate and lead to death. Archimedes Plutonium www.iw.net/~a_plutonium whole entire Universe is just one big atom where dots of the electron-dot-cloud are galaxies PRION DISEASE --------------------------------------------------------------------- (1) Proteins gone awry involved -- Prion protein PrP -------------------------------------------------------------------- (2) Function of proteins gone awry -- transport copper out of brain or body -------------------------------------------------------------------- (3) Metals found in those proteins gone awry -- copper, zinc manganese? -------------------------------------------------------------------- (4) Site or Location of brain where this disease unfolds -- -------------------------------------------------------------------- (5) Pathology of disease -- Similar to Alzheimers in a garbage dump buildup of the PrP protein that strangles or suffocates the brain --------------------------------------------------------------------- (6) When was the first reliably known case -- mid 1900s in New Guinea with Kuru --------------------------------------------------------------------- (7) Statistical incidences of Prion in the general population -- Rare --------------------------------------------------------------------- (8) Age of its victims -- Usually starts after 60 --------------------------------------------------------------------- (9) Geography of disease prevalence -- England in Europe has the highest density Canada in North America and the Rocky Mtn region of USA has highest density in North America ---------------------------------------------------------------------- (10) Any mass spectroscopy of brain tissue of disease or of the hair of diseased victims and what metals were found -- ----------------------------------------------------------------------- (11) Any chemicals that may relieve the disease pathology -- ----------------------------------------------------------------------- (12) Toxic metals that are hypothesized by AP as the root cause: Organic mercury in conjunction with cesium and rubidium ----------------------------------------------------------------------- Archimedes Plutonium www.iw.net/~a_plutonium whole entire Universe is just one big atom where dots of the electron-dot-cloud are galaxies SCHIZOPHRENIA DISEASE (note, I used Wikipedia as a main source for much of the below table) --------------------------------------------------------------------- (1) Proteins gone awry involved -- dopamine -------------------------------------------------------------------- (2) Function of proteins gone awry -- neurotransmitter, sort of like the wires in electricity as an analogy -------------------------------------------------------------------- (3) Metals found in those proteins gone awry -- Not in those proteins, but it was found that zinc ions behave similar to the neurotransmitter of dopamine -------------------------------------------------------------------- (4) Site or Location of brain where this disease unfolds -- striatum, frontal lobes, hippocampus, and temporal lobes -------------------------------------------------------------------- (5) Pathology of disease -- affects the amount of dopamine and a blocking of dopamine pathways --------------------------------------------------------------------- (6) When was the first reliably known case -- 1893 by Kraepelin --------------------------------------------------------------------- (7) Statistical incidences of Prion in the general population -- 7.5 and 16.3 cases per year per 100,000 population --------------------------------------------------------------------- (8) Age of its victims -- Usually starts in the teenager years for males and in the 20s for females --------------------------------------------------------------------- (9) Geography of disease prevalence -- worldwide, but I suspect a concentration by geography where there is alot of mercury in the environment ---------------------------------------------------------------------- (10) Any mass spectroscopy of brain tissue of disease or of the hair of diseased victims and what metals were found -- ----------------------------------------------------------------------- (11) Any chemicals that may relieve the disease pathology -- phenothiazines ----------------------------------------------------------------------- (12) Toxic metals that are hypothesized by AP as the root cause: Organic mercury in conjunction with possibly silver ----------------------------------------------------------------------- Archimedes Plutonium www.iw.net/~a_plutonium whole entire Universe is just one big atom where dots of the electron-dot-cloud are galaxies > SCHIZOPHRENIA DISEASE > [quoted text clipped - 5 lines] > > dopamine I guess technically, dopamine is not a protein. > -------------------------------------------------------------------- > [quoted text clipped - 60 lines] > > ----------------------------------------------------------------------- For some years I thought Schizophrenia had a high rate in wealthy families and so I suspected silver. But making some searches I find that had no evidence. But it is known that zinc ions act like dopamine. So I wonder if zinc is connected to mercury as a cause of Schizophrenia. And I cannot escape the links of Autism as a infant's form of Alzheimers, and Schizophrenia as a teenagers form of Parkinson, where mercury is the culprit in all four diseases. For it is known that in Parkinson there is damage to the dopamine pathways, likewise for Schizophrenia. So the overall picture is that if you get mercury into the brain when a baby, you may end up with Autism, and this same mercury over a lifetime ends up as Alzheimers. And a different mercury in teenagers may end up with Schizophrenia, and that same mercury over a lifetime ends up as Parkinson. Now all of the above would be easily and simply proven true if medical science did mass spectroscopy on diseased patients for mercury analysis. And also, an interesting supporting evidence would be the geography data. If it turns out that some state such as Utah has the highest rates of a number of these diseases, then that would strongly indicate the environment and the presence of mercury as a cause. Archimedes Plutonium www.iw.net/~a_plutonium whole entire Universe is just one big atom where dots of the electron-dot-cloud are galaxies Chapters of this new book: (1) Preface & Introduction (2) Analogy disease of Asbestosis (3) Alzheimers (4) Autism (5) Parkinsons (6) Prion (7) Schizophrenia (8) how to medically prove the assertions of this book-- mass spectroscopy of brain tissue The proof is obvious. That we find mercury in the body of people with these 5 diseases, and we have the protein reactions all figured out. That would mean mass spectroscopy of brain tissue of affected persons. And it would mean a complete detailed analysis of the proteins gone awry, or protein like substances such as dopamine. Mass spectroscopy of hair for mercury is not enough. And medical science is just beginning to do mass spectroscopy of disease tissue looking for mercury, cesium, rubidium and other toxic metals. It is funny how we routinely test for mercury in drinking water but never routinely test for mercury in diseases of these 5 diseases. Now in that table format of those 5 diseases, under the Prion disease is the fact that the prion protein PrP has contained inside itself atoms of copper and zinc for the purpose of this protein is to transport copper and zinc in the brain. So is the purpose of alpha-synuclein some transport of a metal, and does alpha-synuclein have metal atoms as components of this protein? Is the purpose of tau protein or beta amyloid protein in Alzheimer some metal transport function and does it have metal atoms as its structure? When you make tables of these 5 diseases, the tables force us to ask questions that are important questions. So how would mercury atoms interact with Prion proteins? Would the mercury replace the copper atom or bond with the copper atom? A help in the proving of this theory for these 5 diseases is the geography of rates of cases. If it is found that Utah has one of the highest rates of all 5 diseases, and considering that Utah is one of the worst mercury air pollution places due to Nevada mining activities and coal fired electric power plants; would be a supporting evidence of proof that mercury is the main culprit. And in Europe, apparently England has one of the highest rates of all 5 of these diseases, especially prion, and of course, England burns alot of coal to make electricity. So the geography aspect is a important supporting evidence for proof. But the proof will come when the metals are found in the tissues and when those protein pathology is worked out. And going back to the Asbestosis Disease. We knew what the substance that causes the disease and only had to figure out the tissue pathology to explain Asbestosis. One of the huge hindrances to knowing these 5 diseases is the desire for alot of commercial interests to avoid lawsuits such as the drug companies with their mercury laden preservative Thimerosal for infant vaccines which may have caused thousands of cases of Autism. Or the mercury used in farm industry pesticides or fungicides or seed which could cause Parkinson. Or the mercury used in switches or lamps or dental fillings. Or coal fired power plants that emit mercury into the air we breathe. We saw how alot of companies were lawsuited over asbestos, and imagine the lawsuits over Autism Alzheimers, Parkinsons, Schizophrenia and Prion. So there is a strong desire to keep hush hush and to suppress anyone with a theory that mercury is the main culprit. Archimedes Plutonium www.iw.net/~a_plutonium whole entire Universe is just one big atom where dots of the electron-dot-cloud are galaxies Information without understanding is useless. You need to have a much better background that what you are getting from Wikipedia. To start with, dopamine is a catecholamine, not a protein. There are many excellent books on neuroscience, like the _Principles_of_Neuroscience_ by Kandel, Swartz and Jessell. Jeff > SCHIZOPHRENIA DISEASE > [quoted text clipped - 75 lines] > whole entire Universe is just one big atom > where dots of the electron-dot-cloud are galaxies |
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