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Natural Science Forum / Biology / Paleontology / March 2006



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What is Irreducible Complexity?

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ceb_luv_lotr - 03 Mar 2006 18:10 GMT
Irreducible Complexity is a term invented and used by modern
Biochemists to explain the complexity of the cell and how all the parts
work together. In order for the cell to produce the function it needs
to every single part is essential. One of the most common ways that
Irreducible Complexity is used is in the flagellum on some kinds of
single-celled bacteria.
The flagellum on the bacteria appears to most like a whip spinning in
circles in order to propel this single-celled organism into the
direction it needs to go. With the use of this simple "tail", the
bacteria can easily move forward and backward going up to three times
it's own body length in a second. The flagellum can also very quickly
stop and change directions at any time.
When looking at the bacteria's flagellum from the outside, we can see
the filament looking like a long tail, and the hook which attaches the
filament to the bacteria. When looking underneath the surface we then
see that the hook is attached to an L ring and a P ring. These are then
attached to an S ring and an M ring surrounded by a C ring and a ring
of studs. All of this--S ring and M ring (rotor), studs and C ring
(stator), L ring and P ring (bushing)--are held in place by the
membrane that surrounds the cell. If one of these parts is missing, the
entire flagellum does not work. All that happens is the filament lies
dead. Pointless, useless, giving the single-celled organism a huge
weight at one end and no way to move.

Resources:
- http://www.millerandlevine.com/km/evol/design2/article.html
- www.arn.org/docs/ mm/flag_labels.htm
- "Unlocking the Mystery of Life" (video) www.illustramedia.com
Mark VandeWettering - 03 Mar 2006 18:15 GMT
["Followup-To:" header set to talk.origins.]

> Irreducible Complexity is a term invented and used by modern
> Biochemists to explain the complexity of the cell and how all the parts
> work together.

Actually, one biochemist.  And not a very good one.

[ snipped the description of the harbinger of God's glory, the bacterial
 flagellum ]

Hallelujah!

    Mark
Noone Inparticular - 03 Mar 2006 18:17 GMT
> Irreducible Complexity is a term invented and used by modern
> Biochemists to explain the complexity of the cell and how all the parts
> work together.

Wow. One sentence at least six errors. Amazing.

<snip rest>
Grandbank - 04 Mar 2006 04:25 GMT
> Wow. One sentence at least six errors. Amazing.

Creationists revel in ignorance.  They wallow in it.  They fling it in
the air, and rub it on themselves like demented monkeys that have just
discovered the latrine at a banana eating contest.

Ken Phelps
Matt Silberstein - 03 Mar 2006 18:21 GMT
>Irreducible Complexity is a term invented and used by modern
>Biochemists to explain the complexity of the cell and how all the parts
>work together.

Wow, is that deceptive. It is a term invented and used by *a* (one, 1,
singular, solitary) biochemist by the name of Behe. It explains
nothing, it is just sort of an assertion, a classification.

>In order for the cell to produce the function it needs
>to every single part is essential.

That is *not* the claim that Behe makes. Which is good because it is
even more wrong than his claims.

>One of the most common ways that
>Irreducible Complexity is used is in the flagellum on some kinds of
>single-celled bacteria.

Common as in the primary way Behe uses to obfuscate (almost the
opposite of explain) in his book.

>The flagellum on the bacteria appears to most like a whip spinning in
>circles in order to propel this single-celled organism into the
[quoted text clipped - 13 lines]
>dead. Pointless, useless, giving the single-celled organism a huge
>weight at one end and no way to move.

Which is not an explanation and not an argument and says nothing about
evolution.

>Resources:
>- http://www.millerandlevine.com/km/evol/design2/article.html
>- www.arn.org/docs/ mm/flag_labels.htm
>- "Unlocking the Mystery of Life" (video) www.illustramedia.com

Did you even bother to look at Behe' book?
Signature

Matt Silberstein

Do something today about the Darfur Genocide

http://www.beawitness.org
http://www.darfurgenocide.org
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"Darfur: A Genocide We can Stop"

Elf M. Sternberg - 03 Mar 2006 18:36 GMT
> Irreducible Complexity is a term invented and used by modern
> Biochemists to explain the complexity of the cell and how all the
> parts work together.

The concept of Irreducible Complexity is ignored or rejected by the
majority of the scientific community. This rejection stems from the
following: the concept utilises an argument from ignorance, Behe fails
to provide a testable hypothesis, and there is a lack of evidence in
support of the concept. As such, Irreducible Complexity is seen by the
supporters of evolutionary theory as an example of creationist
pseudoscience, amounting to a God of the gaps argument.  

Niall Shanks and Karl H. Joplin have shown that systems satisfying
Behe's characterization of irreducible biochemical complexity can arise
naturally and spontaneously as the result of self-organizing chemical
processes. They also assert that what evolved biochemical and molecular
systems actually exhibit is redundant complexity-- a kind of complexity
that is the product of an evolved biochemical process. They claim that
Behe overestimated the significance of irreducible complexity because
his simple, linear view of biochemical reactions results in his taking
snapshots of selective features of biological systems, structures and
processes, while ignoring the redundant complexity of the context in
which those features are naturally embedded and an overreliance of
overly simplistic metaphors such as his mousetrap. In addition, it has
been claimed that computer simulations of evolution demonstrate that it
is possible for irreducible complexity to evolve naturally.

Elf
Ray - 04 Mar 2006 07:53 GMT
>Niall Shanks and Karl H. Joplin have shown that systems satisfying
>Behe's characterization of irreducible biochemical complexity can arise
>naturally and spontaneously as the result of self-organizing chemical
>processes.

What is evolutionary possible at one level of complexity is not
necessarily possible at higher levels. For each level of complexity,
the improbability of something specific happening by random mutation
increases exponentially. There is quite a step between self-organizing
chemical processses and a flagellum.

Also, adaptability and compatibility between merging subsystems
decreases drastically with increasing complexity and specificness.
Robert Carnegie - 04 Mar 2006 11:59 GMT
> >Niall Shanks and Karl H. Joplin have shown that systems satisfying
> >Behe's characterization of irreducible biochemical complexity can arise
[quoted text clipped - 9 lines]
> Also, adaptability and compatibility between merging subsystems
> decreases drastically with increasing complexity and specificness.

Blabble.  "specificness" isn't even a word.
BarryAC - 04 Mar 2006 12:34 GMT
re "specificness". Neither was "normalcy" a word, but it seems to have taken
the place of "normality". I trust no-one will cite this as an example of
evolution. Barry AC.
Tim K. - 04 Mar 2006 21:22 GMT
>>Niall Shanks and Karl H. Joplin have shown that systems satisfying
>>Behe's characterization of irreducible biochemical complexity can arise
[quoted text clipped - 6 lines]
> increases exponentially. There is quite a step between self-organizing
> chemical processses and a flagellum.

Ah, probability.
This morning the temperature was 60.  By noon it was 76.  What is the
probability that at some point in time today it was 70 degrees?

> Also, adaptability and compatibility between merging subsystems
> decreases drastically with increasing complexity and specificness.

That doesn't even make sense.
Friar Broccoli - 05 Mar 2006 01:02 GMT
>> Niall Shanks and Karl H. Joplin have shown that systems
>> satisfying Behe's characterization of irreducible biochemical
>> complexity can arise naturally and spontaneously as the result
>> of self-organizing chemical processes.

[...  snipped ....]

> For each level of complexity, the improbability of something
> specific happening by random mutation increases exponentially.

While this appears plausible, a bit of consideration shows the
opposite is almost certainly true in practice.  The organisms
that existed 3.7 billion years ago were so extremely simple
that they didn't have a lot to work with.  But over hundreds of
millions of years they gradually developed all sorts of little
bits and pieces like: improved membranes, ion transport
mechanisms, skeletons, shells, hairs, fins, nervous system,
magnetic, vibration, chemical and light sensors etc etc.

Each of these subunits can be looked at like one part of a Lego
set, or module that can be combined with another modules to make
something new and interesting.  Thus with a larger tool kit
evolution can proceed much faster.

Indeed looking at the fossil record this appears to be exactly
what happened.  Up until about a billion years ago not a lot
appeared to be happening, and not very fast.  Then we
started seeing more types of cells.  For example we first see a
calcium shelled amoeba at about 750 million years (in the
Grand Canyon), then at about 590 million years we see the first
traces of multicellular organisms probably early ancestors of
Jellyfish and sponges (at Doushantou in China)

At about 530 million years we have evidence of the first
jointed animals, with the first Trilobite making its entrance
at 520 million years, by which time, we find what appear to be
representatives of all modern groups, although we are still a
very long way from seeing land plants and animals.

So, in summary for the first 3 billion years we don't see much
happening.  Things start getting interesting at about 750
million years and then pandemonium breaks out with the
beginning of the Cambrian at 540 million years.  Sadly, I must
inform you that the last Trilobite cast off its earthly burden about
250 million years ago.  But it put on a good show, having
spawned more than 15,000 species in the intervening 270 million
years.

So, in short, the fossil record appears to tell us that
evolution accelerates as creatures accumulate more and
developmental subunits or modules.

> There is quite a step between self-organizing chemical
> processses and a flagellum.

John Harshman's post pointed to a detail description of how it
might be done:

 http://www.talkdesign.org/faqs/flagellum.html

And my main response contained a much simplified description of how
it might occur:

 http://groups.google.com/group/talk.origins/msg/46d1c15a3a8d22a7

If after reading them, you remain unconvinced, I would be happy
to discuss the question further with you.

> Also, adaptability and compatibility between merging subsystems
> decreases drastically with increasing complexity and specificness.

As my description of the fossil record above mentioned, the
subsystems are better viewed as modules, which evolutionary
processes can use as a tool kit to increase the rate of
development.

Cordially;

Friar Broccoli
Robert Keith Elias, Quebec, Canada  Email: EliasRK (of) gmail * com
Best programmer's & all purpose text editor: http://www.semware.com

--------- I consider ALL arguments in support of my views ---------
TomS - 03 Mar 2006 18:54 GMT
"On 3 Mar 2006 10:10:47 -0800, in article
<1141409447.677945.35170@i39g2000cwa.googlegroups.com>, ceb_luv_lotr stated..."

>Irreducible Complexity is a term invented and used by modern
>Biochemists to explain the complexity of the cell and how all the parts
[...snip...]

   The concept of "irreducible complexity" long predates its use as
an anti-evolutionary argument.

   I've seen it used as early as 1712, as an argument against the
development of the embryo, and for the pre-existence of each
individual living thing (created, individually, back at the
beginning).

   This is just another example of a complaint which is advertised
as being anti-evolution, but - quite aside from whether it is a good
argument - is better recognized as having something like development
as its target.

   (Of course, development is real - just as real as evolution -
so the complaint must have some fatal flaw.)

Signature

---Tom S. <http://talkreason.org/articles/chickegg.cfm>    
"It is not too much to say that every indication of Design in the Kosmos is so
much evidence against the Omnipotence of the Designer. ... The evidences ... of
Natural Theology distinctly imply that the author of the Kosmos worked under
limitations..."                            John Stuart Mill, "Theism", Part II

Cubist - 03 Mar 2006 18:55 GMT
[snippage]

> Irreducible Complexity is a term invented and used by modern
> Biochemists to explain the complexity of the cell and how all the parts
> work together.
  "Explain the complexity of the cell"? Hmmm... no, I disagree.
Irreducible Complexity isn't an *explanation* of "anything*; rather, IC
is a quality that some pieces of the machienry of life are supposed to
have. "The flagellum is IC" is no more an *explanation* of *anything*
than, say, "The sky is blue" or "Water is wet". Rather, "The flagellum
is IC" is, at best, an *observation*, and perhaps an observation which
*needs* an explanation -- but that observation, in and of itself, is
*not* an explanation.

> In order for the cell to produce the function it needs
> to every single part is essential.
  Ah; I see that you accept Behe's definition of Irreducible
Complexity. Dembski has a rather different definition for Irreducible
Complexity; if I may ask you, on what grounds do you accept Behe's
version of IC over Dembski's version of IC?

> One of the most common ways that
> Irreducible Complexity is used is in the flagellum on some kinds of
> single-celled bacteria. ...
  Okay, fine, the flagellum is IC. So what? If you mean to imply "IC,
therefore Designed and not evolved", it's worth noting that *by
(Behe's) definition*, an IC system is one which stops working the
moment *any* of its parts breaks -- in other words, an IC system is
*brittle*. Not robust at all. Fragile and vulnerable, even.
   Imagine, if you will, that you're behind the wheel of an IC
automobile. There you are, driving down the highway, when suddenly the
engine dies! You of course step on the brake and steer towards the side
of the road, but -- alas! -- the brakes *and* steering *both* died with
the engine. You try to put your hazard lights on, but only succeed in
adding "hazard lights" to the growing list of functions which stopped
working when the engine died.
  Fortunately, everyone else on the road manages not to collide with
your disabled hulk of a vehicle, so you survive to (eventually) learn
what the heck *happened* which *made* your vehicle a disabled hulk: A
fuse burned out. Since your vehicle *was* IC, and an IC system is one
for which *all* parts *must* be functional in order for the the system
to work... well, *everything* stopped working. Thus, to the extent that
IC actually does imply a Designer, it implies that this Designer isn't
especially *competent*...
  The competence of the Designer isn't a problem for evolution, of
course. Neither is IC -- one general evolutionary pathway to IC is to
start with a *non*-IC system and lose parts of it until what's left
*is* IC.
CreateThis - 03 Mar 2006 20:48 GMT
> Irreducible Complexity is a term invented and used by modern
> Biochemists to explain the complexity of the cell and how all the parts
[quoted text clipped - 22 lines]
> Resources:
> - http://www.millerandlevine.com/km/evol/design2/article.html

Why do you suppose the trollbot added Miller's *rebuttal* of the IC
argument as a 'resource'?

CT
ceb_luv_lotr - 03 Mar 2006 21:23 GMT
Ok, I appologize. I am not perfect and do not know everything.

Can we please cut back on the rude and sarcastic comments? (ex--"...but
really that post was bad, bad, badly bad." -Noone Inparticular)
especially since you need to remember that the people who write these
posts read them also. You can argue your points all you want, that's
wonderful! That's what I want. Just please do not do it in a way that
is hurtful.

Also, please know that I was not trying to argue Intelligent Design or
Creation. I was merely trying to answer a question that was asked
somewhere else and had a poor answer attached to it.

Again, I appologize for not knowing everything about this. I'm working
on learning more.

Thank you :)
Noone Inparticular - 03 Mar 2006 21:45 GMT
> Ok, I appologize. I am not perfect and do not know everything.

I apologize as well. You appear to not be an IDiot, just someone
unfamiliar with the routine here at T.O. No shame in that. Next time,
make an effort to be up front about your intentions. It'll help stop
knuckleheads like me from jumping all over you.

> Can we please cut back on the rude and sarcastic comments? (ex--"...but
> really that post was bad, bad, badly bad." -Noone Inparticular)

Uh huh. Again, sorry. But you'd be amazed at the inanity we see here on
a daily basis. Look at the recent "Loon Census" thread, pick any name
out of the starting lineup and read some of their posts. Have a barf
bag handy.

> especially since you need to remember that the people who write these
> posts read them also. You can argue your points all you want, that's
[quoted text clipped - 7 lines]
> Again, I appologize for not knowing everything about this. I'm working
> on learning more.

Good on you. Keep doing that.

> Thank you :)
BarryAC - 03 Mar 2006 21:54 GMT
Browsing the websites on both sides of the debate (I too am new to this
surfing) I notice that emotive reactions are mostly from the evolutionists,
spoiling what could be, like this thread, a balanced and informative
discussion. Of course there are crazies amongst the creationists (notice my
gaff earlier re "R. Dawkins"), but far better to ignore all of them, on both
sides, than respond with "who can say the craziest thing!" Keep sane, keep
calm, God bless us all. Barry AC.
Ray - 04 Mar 2006 08:13 GMT
>Browsing the websites on both sides of the debate (I too am new to this
>surfing) I notice that emotive reactions are mostly from the evolutionists,
>spoiling what could be, like this thread, a balanced and informative
>discussion.

Yea, I've noticed that too. It doesn't exactly increase people's
credibility to use such "arguments".
Ken Shaw - 05 Mar 2006 03:34 GMT
> >Browsing the websites on both sides of the debate (I too am new to this
> >surfing) I notice that emotive reactions are mostly from the evolutionists,
[quoted text clipped - 3 lines]
> Yea, I've noticed that too. It doesn't exactly increase people's
> credibility to use such "arguments".

It always amazes me when some creationist shows up, spouts the same old
tired disproven arguments, dumps a little ad hominen and then claims
that the other side is mean spirited. On those rare occasions when a
creationist himself isn't hurling insults with every post they
completely ignore the failings of their own side when chastising the
other.

I'm sure the supporters of science will tone down the insults etc. when
the creationist stop trying to blame the Holocaust, Communism and every
other perceived evil of modern history on the ToE; stop claiming that
you can't be christian if you accept the ToE; posting the same old
tired drivel that AiG said years ago your side should stop using; cease
filling up many kbytes of bandwidth with self refential posts; actually
read evidence when it is presented and make an honest effort to
understand it and finally stop hurling insults at the other side.

Ken
BarryAC - 05 Mar 2006 11:36 GMT
To Ken. "Touche'!" As I have said before, most posts in this group are in
the conflict arena, but there are other arenas in which to hold this debate
(science/religion interface, as I like to call it. Creationism/evolutionism
invites a war of ideologies). Sorry no reference yet, but M. Poole of King's
College London has done much work on this. Barry AC.
Tim K. - 05 Mar 2006 12:19 GMT
> I'm sure the supporters of science will tone down the insults etc. when
> the creationist stop trying to blame the Holocaust, Communism and every
[quoted text clipped - 6 lines]
>
> Ken

What he said!
explainer - 03 Mar 2006 23:07 GMT
> Ok, I appologize. I am not perfect and do not know everything.
>
[quoted text clipped - 4 lines]
> wonderful! That's what I want. Just please do not do it in a way that
> is hurtful.

If you can't take playing with the big boys you may want to try another
group like talk.nothing

You may also benefit from the attitude that "what you think of me and
my ideas is none of my business."

I have learned more for the less than gentle intellects here than the
marshmallows.  Gird up your emotional loins and wade in.

> Also, please know that I was not trying to argue Intelligent Design or
> Creation. I was merely trying to answer a question that was asked
> somewhere else and had a poor answer attached to it.
>
> Again, I appologize for not knowing everything about this. I'm working
> on learning more.

Why don't you know everything about this?  There are several who do
(not me).  I'm like Sgt. Schultz, "I know nothing, nothing."

Hang in there.  It doesn't hurt to insert qualifiers when you are
uncertain.  Asking a question is a good move.

I started a post on the origin of species with a really dumb example
(and got nailed for it), but I also got more instruction than I could
comprehend, almost more than my teeny tiny intellect could endure.

It's at
http://groups.google.com/group/talk.origins/browse_frm/thread/b9c8f31a2225d091/3
b4a380f3c44ee8a?lnk=st&q=&rnum=34#3b4a380f3c44ee8a


I offer this as an example of what can happen when I get my ego out of
the way and seek new knowledge.

Also, some of the posters are real leg pullers.  You never know when
someone is trying to scald you and when they are just having some fun.
(Well, you do know with some of them who have no sense of humor and see
themselves as the axis mundi of universal knowledge.)

All the best, Gordon Hill
CreateThis - 04 Mar 2006 02:02 GMT
> Ok, I appologize. I am not perfect and do not know everything.
>
[quoted text clipped - 13 lines]
>
> Thank you :)

Explanation-free regurgitation of common, lame and nonsensical
antievolution arguments is exactly what nutcase antievolutionist trolls
do here every day.  Maybe you aren't one, but everything you've done so
far fits.

CT
Friar Broccoli - 05 Mar 2006 22:01 GMT
> > Ok, I appologize. I am not perfect and do not know everything.
> >
[quoted text clipped - 13 lines]
> >
> > Thank you :)

> Explanation-free regurgitation of common, lame and nonsensical
> antievolution arguments is exactly what nutcase antievolutionist trolls
> do here every day.  Maybe you aren't one, but everything you've done so
> far fits.

I just found this post by "ceb_luv_lotr":

http://groups.google.com/group/sci.bio.paleontology/msg/112816f9468a9537

I believe it conclusively contradicts the "fit".

Cordially;

Friar Broccoli
Robert Keith Elias, Quebec, Canada  Email: EliasRK (of) gmail * com
Best programmer's & all purpose text editor: http://www.semware.com

--------- I consider ALL arguments in support of my views ---------
Friar Broccoli - 04 Mar 2006 02:31 GMT
[... most of message snipped ...]

> If one of these parts is missing, the entire flagellum does
> not work. All that happens is the filament lies dead.
> Pointless, useless, giving the single-celled organism a huge
> weight at one end and no way to move.

There is one very large problem with Behe's argument.  It implies
that the flagellum popped into existence complete and ready to
fulfill its current function.  This is not how the evolution of
complex devices like the eye or flagellum are thought to occur.

Rather they are thought to be created gradually as parts which
were initially used for OTHER purposes are gradually
accumulated by the organism over many millions of years of
evolution.

The flagellum is basically a hole, a rotating doorway around
the hole, and a tube sticking through the hole which is
rotated by the enclosing doorway.

- The hole is obviously not a problem.  If bacteria didn't have
  holes they couldn't "eat" or remove waste or eject poison
  etc.

- The hollow shaft sticking out of the hole is just as
  obviously not a problem.  It could have evolved as a type of
  foot, or stem for holding onto things.  Maybe it was used as
  a spear for sticking into other bacteria to kill them and
  suck out the contents etc.  Stick like appendages have all
  sorts of interesting uses, so lots of different types would
  have evolved in lots of different ways.

- So that leaves the rotating bit, and as it turns out, that's
  not a problem either.  Most cells already have rotating
  doorways to help transfer things across cell walls.

  So its just a matter of coupling together the shaft with a
  rotating doorway, a relatively minor mutation.  Initially the
  rotation would have been very inefficient, but 2 billion
  years ago (or whenever flagellum started to evolve) nothing
  had a good moveable arm/stick/flagellum so any bacteria that
  had even a poorly functioning one would have had an advantage
  over his completely stationary neighbours.

  After that you just add a billion years of evolution
  (bacteria have been evolving for more than 3 billion years)
  and you get the insanely beautiful flagellum that we see
  today.

  It is true that if you took out any part TODAY, the current
  version wouldn't work at all, but it got that way via lots
  of small changes over a very long period of time.

And remember, we've got about
1,000,000,000,000,000,000,000,000,000,000 bacteria on earth
right now and each day or so most of them will divide, and a
lot of them will have a small mutation that may improve their
performance.  Over billions of years, that many bacteria working
that hard are bound to accomplish some interesting stuff.

I hope this helps clarify things for you.

Cordially;

Friar Broccoli
Robert Keith Elias, Quebec, Canada  Email: EliasRK (of) gmail * com
Best programmer's & all purpose text editor: http://www.semware.com

--------- I consider ALL arguments in support of my views ---------
anon1@sci.sci - 04 Mar 2006 04:21 GMT
<http://groups.google.com/group/talk.origins/msg/46d1c15a3a8d22a7>
= Message-ID: <1141439483.876961.119310@i40g2000cwc.googlegroups.com>
> The flagellum is basically a hole, a rotating doorway around
> the hole, and a tube sticking through the hole which is
> rotated by the enclosing doorway.

> - The hole is obviously not a problem.  If bacteria didn't have
>   holes they couldn't "eat" or remove waste or eject poison
>   etc.

> - The hollow shaft sticking out of the hole is just as
>   obviously not a problem.  It could have evolved as a type of
[quoted text clipped - 3 lines]
>   sorts of interesting uses, so lots of different types would
>   have evolved in lots of different ways.

> - So that leaves the rotating bit, and as it turns out, that's
>   not a problem either.  Most cells already have rotating
>   doorways to help transfer things across cell walls.

>   So its just a matter of coupling together the shaft with a
>   rotating doorway, a relatively minor mutation.  Initially the
[quoted text clipped - 3 lines]
>   had even a poorly functioning one would have had an advantage
>   over his completely stationary neighbours.

>   After that you just add a billion years of evolution
>   (bacteria have been evolving for more than 3 billion years)
>   and you get the insanely beautiful flagellum that we see
>   today.

That's the best rebuttal I've read in a long time. I cited the GGURL
and message-ID in case somebody wants to link it from one of the FAQs,
and I quoted the whole good part so more people would chance to see it.

>   It is true that if you took out any part TODAY, the current
>   version wouldn't work at all, ...

Actually depending on what part you took out, it might still work, not
the same as with all parts, maybe not the same function at all, but
some other function might still occur. So I didn't include that in the
"best rebuttal" quote above.
.
Friar Broccoli - 04 Mar 2006 16:21 GMT
> That's the best rebuttal I've read in a long time.

Thanks.

Cordially;

Friar Broccoli
Robert Keith Elias, Quebec, Canada  Email: EliasRK (of) gmail * com
Best programmer's & all purpose text editor: http://www.semware.com

--------- I consider ALL arguments in support of my views ---------
Noone Inparticular - 04 Mar 2006 16:29 GMT
> [... most of message snipped ...]
>
[quoted text clipped - 20 lines]
>    holes they couldn't "eat" or remove waste or eject poison
>    etc.

Erm, Brother Vegetable, don't confuse the lad. If bacteria really had
holes in their membranes they be dead. They'd be unable to maintain ion
gradients, required for life. Better to say "pore" rather than hole as
a pore has a closure that prevents the equilibration of the salts in
the cytosol with the envrionment while still allowing things to pass
through the membrane.

Didactically yours

NI

>  - The hollow shaft sticking out of the hole is just as
>    obviously not a problem.  It could have evolved as a type of
[quoted text clipped - 41 lines]
>
>  --------- I consider ALL arguments in support of my views ---------
John Harshman - 04 Mar 2006 17:49 GMT
>>[... most of message snipped ...]
>>
[quoted text clipped - 27 lines]
> the cytosol with the envrionment while still allowing things to pass
> through the membrane.

Hmmm. If that's true, then what am I doing when I make competent
bacteria for cloning? I always thought I was putting little holes in
their cell membranes.

Ever more didactically yours.

[snip]
Noone Inparticular - 04 Mar 2006 22:08 GMT
> >>[... most of message snipped ...]
> >>
[quoted text clipped - 31 lines]
> bacteria for cloning? I always thought I was putting little holes in
> their cell membranes.

I don't know which method you use, but some of the most popular methods
don't involve making holes in cell membranes (cationic lipids and
cationic precipitation) and the most commonly used method that does put
holes in cell membranes, electroporation, results in holes whose
existence is measured in milliseconds. Far to short a time for
diffusion of salts, but more than adequate for transfer of nucleic
acids.

When you are facing a bacterial infection in your body, one of the most
effective inate mechanisms to kill the infection results from the
formation of stable perforations in the cell membranes. The complex of
proteins which does it, perforin, is the product of the complement
system. The stable perforations make it impossible for the cell to
control the concentrations of salts within it, thus killing the cells.

How's THAT for didactic?

> Ever more didactically yours.
>
> [snip]
John Harshman - 04 Mar 2006 22:48 GMT
>>>>[... most of message snipped ...]
>>>>
[quoted text clipped - 40 lines]
> diffusion of salts, but more than adequate for transfer of nucleic
> acids.

Oh. There's a perfect demonstration that its not necessary to know what
you're doing in order to do biology. I follow the recipe, I get clones,
I sequence the clones. All fine, and no need to know why it works.

> When you are facing a bacterial infection in your body, one of the most
> effective inate mechanisms to kill the infection results from the
[quoted text clipped - 8 lines]
>>
>>[snip]
Noone Inparticular - 05 Mar 2006 21:36 GMT
> >>>>[... most of message snipped ...]
> >>>>
[quoted text clipped - 44 lines]
> you're doing in order to do biology. I follow the recipe, I get clones,
> I sequence the clones. All fine, and no need to know why it works.

You're quite right; much of the business end of many techniques are not
really well understood, even by the people who develop them. Since I
can't seem to avoid being didactic in this thread, I might as well go
on.

It appears that what happens with many of the protocols that use
cationic salts is that if the salt and nucleic acid concentrations are
right, meta-stable complexes between the nucleic acids and salts form.
These complexes mask the net charge on the nucleic acid and since in
the complexes they are essentially non-polar, they precipitate. The
insoluable and partially soluble somewhat non-polar complexes are able
to get across the cell membrane because those high salt conditions also
greatly alter surface dilution kinetics of the membrane. Since they are
largely non-polar in the meta-stable complex, they can diffuse through
the membrane.

With the cationic lipids, it much more straight forward; the cationic
headgroups of the lipids bind the phosphate groups on the nucleic
acids, masking both molecules charges. The non-polar acyl chains do the
rest.

> > When you are facing a bacterial infection in your body, one of the most
> > effective inate mechanisms to kill the infection results from the
[quoted text clipped - 8 lines]
> >>
> >>[snip]
Friar Broccoli - 04 Mar 2006 20:25 GMT
>>  - The hole is obviously not a problem.  If bacteria didn't have
>>    holes they couldn't "eat" or remove waste or eject poison
>>    etc.

> Erm,

 Did you mean Om?

> Brother Vegetable,

Thanks for acknowledging that we are commonly decent.

> don't confuse the lad.

I try to do that by avoiding unimportant technical details.

> If bacteria really had holes in their membranes they be dead.
> They'd be unable to maintain ion gradients, required for life.
> Better to say "pore" rather than hole as a pore has a closure
> that prevents the equilibration of the salts in the cytosol
> with the envrionment while still allowing things to pass
> through the membrane.

I get the impression that ceb_luv_lotr has limited knowledge in
biology, consequently, I believe that the use of the word
"pore" would have added to the confusion, by making an already
complex message just a little bit harder to access.

Also, I'm not even certain I am technically wrong, since a
"pore" is (I believe) simply a hole that is normally closed.

And if I'm wrong about that it appears that John Harshman is
ready to beat up on you.  So I must ask if your cause has aids?

That said, I debated with myself about adding my usual "I am an
idiot" disclaimer.  Still don't know if I should have.

> Didactically yours

That word has too many syllables for use in polite
conversation.

Yours in the holey Broccoli

Friar Broccoli
Robert Keith Elias, Quebec, Canada  Email: EliasRK (of) gmail * com
Best programmer's & all purpose text editor: http://www.semware.com

--------- I consider ALL arguments in support of my views ---------
anon1@sci.sci - 04 Mar 2006 03:31 GMT
> Irreducible Complexity is a term invented and used by modern
> Biochemists to explain the complexity of the cell and how all the parts
> work together.

No, it's a term invented by drop-outs who didn't happen to show up for
class the day of the lecture on "scaffolds" and change of function over
time.

> In order for the cell to produce the function it needs to every
> single part is essential.

Are you talking about the basic essential functions (growth and
replication) needed by every cell, or the complete set of specific
functions a particular cell happens to have currently, which have
undoubtedly changed many times over the ancestral history of that cell?

The basic functions have been the same for at least 3.5 billion years,
carrying us back through the RNA-to-DNA takeover and all the way to the
start of RNA world and probably even earlier. So the fact we can't
quite see how they could exist without each other is no problem for
evolutionary theory.

The complete set of incidental functions don't have IC, so if that's
what you meant then you are flat-out liar.

> The flagellum on the bacteria ...

How does this relate to IC? Some bacteria have flagella, and some get
by just fine without them. They are in no way essential to life.

> If one of these parts is missing, the entire flagellum does not work.

Maybe the thing as a whole doesn't work in the current way, to provide
largescale motion through the water, but the remaining parts still work
in other ways, such as by pumping waste out of the cell.

> All that happens is the filament lies dead. Pointless, useless,
> giving the single-celled organism a huge weight at one end and no way
> to move.

Well if the part that makes the flagellum spin was broken, but the bulk
of the filament was still there, sure. But what if the bulk of the
flagellum was the part that was missing, or greatly shortened, and the
tiny base still spun just fine? Then the cell wouldn't have the problem
you cite. There are in fact some niches where that partial system is
optimal, and we see some cells adapted to that niche even today.

Why do you waste your typing energy beating this same dead horse again?
.
Ray - 04 Mar 2006 06:04 GMT
Quote:

"Anyone can state at any time that they cannot imagine how
evolutionary mechanisms might have produced a certain species, organ,
structure. Such statements, obviously, are personal – and they say
more about the limitations of those who make them than they do about
the limitations of Darwinian mechanisms."

Well lets try to turn that around:

"Anyone can state at any time that they can easily imagine how
evolutionary mechanisms might have produced a certain species, organ,
structure. Such statements, obviously, are personal – and they say
more about the vivid imagination of those who make them than they do
about the actual probable capabilities of Darwinian mechanisms."

CreateThis - 06 Mar 2006 14:49 GMT
> Quote:
>
[quoted text clipped - 11 lines]
> more about the vivid imagination of those who make them than they do
> about the actual probable capabilities of Darwinian mechanisms."

Imagining ways that evolution could work disproves the claim that it
couldn't - and shows the pessimists' imagination to be disfunctional.

But scientists haven't only imagined ways that evolution could work;
they've also shown that it *does* work.  The pessimists have only shown
that they don't *want* it to work.

CT
TomS - 06 Mar 2006 15:13 GMT
"On Mon, 06 Mar 2006 14:49:08 GMT, in article
<EZXOf.66443$PL5.43767@newssvr11.news.prodigy.com>, CreateThis stated..."

>> Quote:
>>
[quoted text clipped - 18 lines]
>they've also shown that it *does* work.  The pessimists have only shown
>that they don't *want* it to work.

   And the "pessimists", they haven't *even* *imagined* the ways
that design could work.
   

Signature

---Tom S. <http://talkreason.org/articles/chickegg.cfm>    
"It is not too much to say that every indication of Design in the Kosmos is so
much evidence against the Omnipotence of the Designer. ... The evidences ... of
Natural Theology distinctly imply that the author of the Kosmos worked under
limitations..."                            John Stuart Mill, "Theism", Part II

Thurisaz the Einherjer - 04 Mar 2006 06:29 GMT
> One of the most common ways that
> Irreducible Complexity is used is in the flagellum on some kinds of
> single-celled bacteria.

One of the most common lies used by the IDiots is the claim that the
bacterial flagellum is irreducibly complex.

Signature

Romans 2:24 revised:  
"For the name of God is blasphemed among the Gentiles through you
cretinists, as it is written on aig."

Why I am not a christian: http://www.carcosa.de/nojebus/nojebus

Ray - 04 Mar 2006 06:51 GMT
quote:

"Irreducibly complex structures, we are told, could not have been
produced by evolution, or, for that matter, by any natural process.
They do exist, however, and therefore they must have been produced by
something. That something could only be an outside intelligent agency
operating beyond the laws of nature – an intelligent designer."

An intelligent designer does not have to operate beyond the laws of
nature, he could simply utilize them in his work (which is actually
what he does).
Ray - 04 Mar 2006 07:24 GMT
quote:

"Unfortunately for this line of argument, the claim that one
irreducibly-complex system might contain another is
self-contradictory. To understand this, we need to remember that the
entire point of the design argument, as exemplified by the flagellum,
is that only the entire biochemical machine, with all of its parts, is
functional. For the intelligent design argument to stand, this must be
the case, since it provides the basis for their claim that only the
complete flagellum can be favored by natural selection, not any its
component parts.

However, if the flagellum contains within it a smaller functional set
of components like the TTSS, then the flagellum itself cannot be
irreducibly complex – by definition. Since we now know that this is
indeed the case, it is obviously true that the flagellum is not
irreducibly complex."

comment:

Obviously, an intelligent designer can place as many IC systems nested
within each other, as he likes (we do ourselves, in our designs).
Their development can be programmed into the original DNA / gene
blueprints, just like anything else in the organism is.
Frank J - 04 Mar 2006 20:59 GMT
> Irreducible Complexity is a term invented and used by modern
> Biochemists to explain the complexity of the cell and how all the parts
> work together.

Except that there's no agreement on the definition. Some scientists say
that certain biochemical systems are irreducibly complex, but can be
prodiced via evolution. Others say that those systems aren't really
irreducibly complex.

While the phrase was used before in biology, pseudoscientists have
hijacked it to pretend that IC invalidates evolution and is "evidence
for design." There's no reason that it would have to be both, of
course, despite the pseudoscientists' assertion to that effect. And in
fact it does neither. And it certainly provides no support for a
potential alternative theory.

But IC-speak fools the public, and that's all the pseudoscientists
really want. I don't know if it was intentional or just a bonus, but
they managed to get their critics to sound confused by not agreeing on
a definition and sticking to it. Nevertheless, it should be no surprise
that, after a decade of IC-speak, the pseudoscientists have not
published one iota of original research that would back up their
grandiose claims.

(snip)
Richard Smol - 04 Mar 2006 21:23 GMT
> Irreducible Complexity is a term invented and used by modern
> Biochemists

*Bzzzzt* ... wrong. It is invented and used by creationists only.
Thanks for playing.

RS
 
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