 |
 | Home | Contact Us | FAQ | Search & Site Map | Link to Us |
 | Sign In | Join | Other 45 Sites in Network |
Natural Science Forum / Chemistry / Organic Synthesis / September 2006Lithium bromide vs Sodium Bromide
Why we use LiCl or LiBr instead of NaCl, NaBr in sythesis? Thanks, Generally, solubility and Lewis acidity. I remember some work out of IU about 20 years ago that used something like 30 % LiClO4 in ether as a reaction medium to accelerate Diels-Alder reactions. I was mostly impressed how soluble it is. Lewis acidity helps accelerate reactions like Sn2 displacements by tugging on the leaving group while the nucleophile pushes from the other side. Eric Lucas |
Reply to this Message |
 Sign In
 Join
 My Latest Posts My Monitored Threads My Blog My Photo Gallery My Profile My Homepage Start New Thread Enable EMail Alerts Rate this Thread
|
©2009 Advenet LLC Privacy Policy - Terms of Use
This website includes both content owned or controlled by Advenet as well as content owned or controlled by third parties.