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Natural Science Forum / Chemistry / Organic Synthesis / February 2004Grignard from chloropyridine
Can chloropyridines be converted to Grignard reagents? I am told that cannot be done. I wonder if that's true.  SignaturePaul J. Franklin(moderator - sci.chem.organic.synthesis) http://organicworldwide.net/sci.chem.organic.synthesis Georgia State University <chepjf@panther.gsu.edu> Atlanta, GA > Can chloropyridines be converted to Grignard reagents? I am told that > cannot be done. I wonder if that's true. Will you get Grignard formation or dissolving metal reduction and/or coupling? One imagines 4-chloropyridine will be very uncooperative. SignatureUncle Al http://www.mazepath.com/uncleal/ (Toxic URL! Unsafe for children and most mammals) "Quis custodiet ipsos custodes?" The Net! -- Paul J. Franklin(moderator - sci.chem.organic.synthesis) http://organicworldwide.net/sci.chem.organic.synthesis Georgia State University <chepjf@panther.gsu.edu> Atlanta, GA |
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