Natural Science Forum / Chemistry / Organic Synthesis / October 2003

Hi..
Can someone tell me how sucrose react with amino acids ? what are the
resulting products?
I know reducing sugars react with amino acids -- maillard reaction.

I am a second semester organic chemistry student.  My class focuses a lot on
organic synthetic pathways.  Most of our synthesis reactions are 5-8 steps.
I've read in our book a little bit about retrosynthesis, in order to help
improve working out the problems, but I was just curious ...

Hi, I'm interested in synthesising some vanillin
(4-hydroxy-3-methoxybenzaldehyde) from eugenol
(1-(4-hydroxy-3-methoxyphenyl)-2-propene, I think) and was wondering what
methods are possible to oxidise 1-(4-acetyl-3-methoxyphenyl)-2-propene to

I have a big problem with this reaction:
1,8-dinitronaphthalene > 1,8-diaminonaphthalene
I attempt to reduce the dinitro with HCl and Fe, but when I put inside NaOH
I have a precipitate like-black-green coloured (maybe Fe(OH)2) and a liquid

I need a procedure to react indole with carbonyl chloride to give
3-substituted indole. I know that this can be done using Grignard
reagent to abstract hydrogen to activate indole ring or just by a
simple reaction of indole with a chloride. I want to avoid Grignard

Need help:
 J. of Labelled Compounds and Radiopharmaceuticals(34(4), 383-90;
1994) reported a method for preparation HOCH2CH2OH (Carbon 11 labeled)
from KCN (C11) in three steps

I need something special. I want to prepare glycidyl acrylate or
better (2,3 epoxy)propyl acrylate (CAS no. 106-90-1). A long time ago
Aldrich offered this substance. Actually I'm looking for a simple and
non-malodorous kind of preparation.

I always thought alkyllithiums react with CO2 to form tertiary alcohols
and Grignard reagents react with CO2 to form carboxylic acids. Then, I
read some references that said alkyllithiums react with CO2 to form
carboxylic acids.  Anyone has any insight into this?

I am trying to get a "quick and dirty" value for the rotational energy
barrier in a CC triple bond.  As a first guess, I would say about
twice the value for a CC double bond.   Any data  that speak
against this or for it?

Marc wrote:

This query was also posted to sci.chem
Hi,
I'm doing a reaction similar to that of Organic Syntheses, CV 4, 234
(see: http://www.orgsyn.org/orgsyn/orgsyn/prepContent.asp?prep=CV4P0234