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Natural Science Forum / Chemistry / Organic Synthesis / January 2004



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ThreadLast Post  Replies
Stability of o-Phthalaldehyde (OPA)28 Jan 2004 20:35 GMT1
I'm currently working with o-Phthalaldehyde  (CAS: 643-79-8) and I am
very interested in knowing the stability of this chemical. On the
bottle is says that this chemical is "Air, light, temperature and
moisture sensitive".
any idea to cleave the methyl ester of this compound?27 Jan 2004 15:01 GMT3
(p-TfO)PhCH(CO2Me)CH(OH)CH2OH. 3x
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Paul J. Franklin(moderator - sci.chem.organic.synthesis)
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Preparation of acrylanilides27 Jan 2004 15:00 GMT2
Have anybody synthesized acrylanilides? I would be very grateful for giving
me any advices and sources about this topic. I'm making this synthesis from
anhydrites and anilines, but I have problems with purifing these compounds.
thanks in advance
medicinal chemistry20 Jan 2004 20:45 GMT2
Im taking med-chem and I was wondering if you had any suggestions to
understanding some of the concepts. i.e. easy way to remember the Kreb
cycle or the different uses for the many functional groups.
thanks a bunch,
Clemmensen reduction of a,b unsaturated aldehyde20 Jan 2004 20:44 GMT3
Can a Clemmensen reduction be used in this example to reduce the aldehyde
group to methyl without affecting the double bond?
R-CH=CH-CHO ->  R-CH=CH-CH3
Thanks
stability of carbokation(?) as in SN1 Reactions20 Jan 2004 20:41 GMT2
first, I am sorry for my bad english, but however i hope that you understand my problem.
Can anyone please sort the following molecules in their stability in the transition state (don't know if that is the right word),
with the first number representing the most stabil carbokation. ...
protein experiments15 Jan 2004 19:11 GMT1
I was wondering if anyone knows of a good experiment to do in a med
chem class that deals with proteins or amino acids. I am looking for a
synthisis, degradation, or extraction. I am open to any sugesstions or
other possibilities.
4-amino salicylaldehyde14 Jan 2004 20:35 GMT1
I was going to synthesize some 7 substituted coumarins starting from
4-salicylaldehydes.  The list of substituents would be chosen so that
I would have a coumarin matching each benzene in the Johnson &
Jankowski 13-C NMR catalog.
Bromination of Cyclopentane12 Jan 2004 17:01 GMT4
Would NBS react to monobrominate cyclopentane, and if so, what
reaction conditions would be ideal?  Chloroform, acetic anhydride,
peroxides, intense light?
Thank You to all who respond!
 
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